{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T03:28:22Z","timestamp":1747193302943,"version":"3.40.5"},"reference-count":17,"publisher":"S. Karger AG","issue":"5-6","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cerebrovasc Dis"],"published-print":{"date-parts":[[2017]]},"abstract":"<b><i>Introduction:<\/i><\/b> Although carotid stenosis can cause both territorial and border-zone (BZ) cerebral infarcts (CI), the influence of CI topography on postoperative complications after surgery remains unclear. We compared early outcomes after endarterectomy on the basis of CI location: territorial (T group) or BZ group. <b><i>Material and Methods:<\/i><\/b> During the period between 2009 and 2013, ischaemic stroke patients who had undergone surgery for symptomatic carotid stenosis were identified from prospective databases from 3 French centres. The outcome was the identification of a combined stroke\/death rate 30 days after endarterectomy. <b><i>Results:<\/i><\/b> Two hundred and eighty-nine patients were included, 216 (74.7%) in the T group and 73 (25.3%) in the BZ group. The mean degree of stenosis was comparable in the 2 groups (78 \u00b1 12% in the T group vs. 80 \u00b1 12% in the BZ group, <i>p<\/i> = 0.105), with, however, more sub-occlusions (stenosis >90%) in the BZ group (38.4 vs. 23.1%, <i>p<\/i> = 0.012). The mean time between the time CI developed and the time surgery was performed was 19.6 \u00b1 24.8 days, with a majority of patients being operated upon within 2 weeks following the formation of CI (66.7% in the T group vs. 60.3% in the BZ group, <i>p<\/i> = 0.322). The combined endpoint was significantly more frequent in the BZ group (9.6 vs. 1.9%, <i>p<\/i> = 0.003), with 4 ischaemic strokes and 3 deaths. In multivariate analysis, BZ CI was an independent predictor of postoperative stroke or death at 30 days (HR 4.91-95% CI [1.3-18.9], <i>p<\/i> = 0.020). <b><i>Conclusion:<\/i><\/b> BZ infarcts carry a greater risk of postoperative complications after carotid surgery, thus suggesting that topography of the CI should be considered in the decision-making process regarding surgery.<\/jats:p>","DOI":"10.1159\/000479934","type":"journal-article","created":{"date-parts":[[2017,9,14]],"date-time":"2017-09-14T21:02:01Z","timestamp":1505422921000},"page":"291-296","source":"Crossref","is-referenced-by-count":0,"title":["Cerebral Infarct Topography and Early Outcome after Surgery for Symptomatic Carotid Stenosis: A Multicentre Study"],"prefix":"10.1159","volume":"44","author":[{"given":"Caroline","family":"Kazandjian","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicla","family":"Settembre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabien","family":"Lareyre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Kretz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agn\u00e8s","family":"Soudry-Faure","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7848-7072","authenticated-orcid":false,"given":"Yannick","family":"B\u00e9jot","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergue\u00ef","family":"Malikov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reda","family":"Hassen-Khodja","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elixene","family":"Jean-Baptiste","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Steinmetz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2017,9,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(97)09292-1"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.30.9.1751"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)15785-1"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2008.11.006"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2012.12.009"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2015.10.097"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.20.7.864"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1053\/ejvs.2002.1946"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(07)70274-0"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/S1479-666X(07)80108-9"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1148\/rg.315105014"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.28.1.118"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/BF00347803"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.36.3.373"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000155727.82242.e1"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1159\/000015903"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.55.11.1475"}],"container-title":["Cerebrovascular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/479934","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/479934","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:50:32Z","timestamp":1745427032000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000479934"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":17,"journal-issue":{"issue":"5-6","published-online":{"date-parts":[[2017,12,5]]},"published-print":{"date-parts":[[2017,12,14]]}},"URL":"https:\/\/doi.org\/10.1159\/000479934","archive":["Portico"],"relation":{},"ISSN":["1015-9770","1421-9786"],"issn-type":[{"type":"print","value":"1015-9770"},{"type":"electronic","value":"1421-9786"}],"subject":[],"published":{"date-parts":[[2017]]}}}