{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T14:18:35Z","timestamp":1785161915559,"version":"3.55.0"},"reference-count":22,"publisher":"S. Karger AG","issue":"3-4","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Nutr Metab"],"published-print":{"date-parts":[[2017]]},"abstract":"<b><i>Background:<\/i><\/b> Vitamin A is an essential nutrient for pregnant women, and other vitamin A-related compounds, including lutein and lycopene, have been associated with maternal-infant outcomes. The objective of this study was to quantify the status of vitamin A and related compounds in maternal-infant pairs at the time of delivery, and to determine its impact on clinical outcomes. <b><i>Methods:<\/i><\/b> Maternal and cord blood samples were collected in 189 mother-infant pairs. Concentrations of lutein + zeaxanthin, \u03b2-cryptoxanthin, lycopene, carotenes, and retinol were measured using high-performance liquid chromatography. Descriptive statistics was calculated and Spearman coefficients were used to assess correlations between maternal and cord measurements. Kruskal-Wallis and independent samples <i>t<\/i> test were used to compare measures between retinol groups. Linear and logistic regression models were used to adjust for relevant confounders. <i>p<\/i> < 0.05 was considered statistically significant. <b><i>Results:<\/i><\/b> Ten percent of mothers had serum retinol concentrations \u22640.70 \u00b5mol\/L; 80% of infants had serum retinol concentrations \u22640.70 \u00b5mol\/L. Low maternal retinol concentrations were associated with maternal anemia (<i>p<\/i> = 0.04) and a trend toward low birth weight (<i>p<\/i> = 0.06). Maternal and infant concentrations of vitamin A compounds were highly correlated. After adjustment for confounders, maternal lutein was associated with a C-section (<i>p<\/i> = 0.03) and a diagnosis of respiratory distress syndrome in the infant (<i>p<\/i> = 0.02). Maternal lycopene was associated with growth parameters in the infant. <b><i>Conclusions:<\/i><\/b> As vitamin A-related compounds are modifiable by diet, future research determining the clinical impact of these compounds is warranted.<\/jats:p>","DOI":"10.1159\/000481292","type":"journal-article","created":{"date-parts":[[2017,9,22]],"date-time":"2017-09-22T21:01:28Z","timestamp":1506114088000},"page":"175-182","source":"Crossref","is-referenced-by-count":22,"title":["Status of Vitamin A and Related Compounds and Clinical Outcomes in Maternal-Infant Pairs in the Midwestern United States"],"prefix":"10.1159","volume":"71","author":[{"given":"Corrine","family":"Hanson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Schumacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Lyden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy","family":"Furtado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Van Ormer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"McGinn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine","family":"Rilett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caleb","family":"Cave","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kara","family":"Weishaar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann","family":"Anderson-Berry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2017,9,22]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(15)00039-X"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD007480.pub3"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.112.034868"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2016.00411"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2002.01010.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199906243402505"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3390\/nu8080508"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s10995-009-0541-7"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1017\/S1368980008002723"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3390\/nu8110669"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/652148"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejcn.1601320"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3016.2012.01284.x"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.13303"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1038\/ejcn.2014.282"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2012.07.109"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2011.87"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1159\/000227291"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1055\/s-0032-1321494"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(03)00040-7"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(01)01437-5"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0135192"}],"container-title":["Annals of Nutrition and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/481292","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/481292","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:00:40Z","timestamp":1745427640000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000481292"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":22,"journal-issue":{"issue":"3-4","published-online":{"date-parts":[[2018,1,11]]}},"URL":"https:\/\/doi.org\/10.1159\/000481292","archive":["Portico"],"relation":{},"ISSN":["0250-6807","1421-9697"],"issn-type":[{"value":"0250-6807","type":"print"},{"value":"1421-9697","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}