{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T13:08:26Z","timestamp":1754399306919,"version":"3.40.4"},"reference-count":15,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2017,10,17]],"date-time":"2017-10-17T00:00:00Z","timestamp":1508198400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2017,10,17]],"date-time":"2017-10-17T00:00:00Z","timestamp":1508198400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Oncol"],"abstract":"<jats:p>Posttransplant lymphoproliferative disorders (PTLD) represent a rare and potentially life-threatening complication after liver transplantation. Classical Hodgkin lymphoma (cHL), with an incidence of approximately 1.8\u20133.4% of all PTLD cases, represents a minority of PTLD, mainly presenting as a late transplant complication. The main risk factors for the development of PTLD are Epstein-Barr virus (EBV) infection and intensive immunosuppression. However, other risk factors like hepatitis C virus may, together with EBV infection, contribute to the development of PTLD. Here we present a case of late-onset EBV-positive cHL that occurred 10 years after an unrelated donor liver transplantation. To our knowledge, this is the first report of cHL occurring with such a long interval after liver transplantation. Given the low incidence of cHL PTLD, there is little information regarding pathology, clinical characteristics, and management of this disease. The development of individual, risk-adapted treatments may improve the long-term outcome of cHL PTLD.<\/jats:p>","DOI":"10.1159\/000481452","type":"journal-article","created":{"date-parts":[[2017,10,17]],"date-time":"2017-10-17T21:08:52Z","timestamp":1508274532000},"page":"923-927","source":"Crossref","is-referenced-by-count":5,"title":["A Rare Case of Classical Hodgkin Lymphoma Diagnosed 10 Years after Liver Transplant"],"prefix":"10.1159","volume":"10","author":[{"given":"L.","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Pereira\u00a0Mestre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Bihl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"B\u00fchler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Vannata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Stathis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2017,10,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1600-6143.2003.00325.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2005.03.015"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3181b9692d"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-6143.2002.21003.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2005.01115.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(07)70040-2"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1053\/jlts.2000.7578"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-07-101956"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-05-158824"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1478-3231.2009.02138.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm.2015.2372"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2001.19.3.772"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.01.0934"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-11-681064"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61469-0"}],"container-title":["Case Reports in Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/481452","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/481452","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/481452","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:01:57Z","timestamp":1745427717000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000481452"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,17]]},"references-count":15,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2018,1,4]]}},"URL":"https:\/\/doi.org\/10.1159\/000481452","archive":["Portico"],"relation":{},"ISSN":["1662-6575"],"issn-type":[{"type":"electronic","value":"1662-6575"}],"subject":[],"published":{"date-parts":[[2017,10,17]]}}}