{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T04:00:39Z","timestamp":1772164839913,"version":"3.50.1"},"reference-count":7,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2017,10,26]],"date-time":"2017-10-26T00:00:00Z","timestamp":1508976000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2017,10,26]],"date-time":"2017-10-26T00:00:00Z","timestamp":1508976000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Oncol"],"abstract":"<jats:p>Extranodal natural killer\/T-cell lymphoma (ENKL), nasal type, is a rare, aggressive non-Hodgkin lymphoma for which no clear standard of care has been established, particularly in the relapsed\/refractory disease setting. Because of its rarity, randomized trials are not conducted specifically on ENKL, nasal type; however, case reports and small case series can provide important insights into potential new treatments. We present a case report of a patient with ENKL, nasal type (previously misdiagnosed as relapsing chronic sinusitis), whose disease progressed during multi-agent chemotherapy but responded to second-line treatment with single-agent pralatrexate. We discuss treatment options for relapsed\/refractory ENKL, nasal type, and suggest that pralatrexate be further evaluated in this clinical setting.<\/jats:p>","DOI":"10.1159\/000481567","type":"journal-article","created":{"date-parts":[[2017,10,26]],"date-time":"2017-10-26T17:02:05Z","timestamp":1509037325000},"page":"948-953","source":"Crossref","is-referenced-by-count":3,"title":["Misdiagnosed Refractory Extranodal Natural Killer\/T-Cell Lymphoma, Nasal Type, Successfully Treated: A Case Report"],"prefix":"10.1159","volume":"10","author":[{"given":"Jos\u00e9\u00a0Domingo","family":"Saavedra\u00a0Ram\u00edrez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2017,10,26]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-017-0452-9"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-01-643569"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.29.9024"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.20.8470"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-12-686147"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.4137\/CMO.S8536"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.23.8592"}],"container-title":["Case Reports in Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/481567","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/481567","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/481567","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T13:03:15Z","timestamp":1745413395000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000481567"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,26]]},"references-count":7,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2018,1,4]]}},"URL":"https:\/\/doi.org\/10.1159\/000481567","archive":["Portico"],"relation":{"is-basis-for":[{"id-type":"doi","id":"10.1159\/000484583","asserted-by":"object"}]},"ISSN":["1662-6575"],"issn-type":[{"value":"1662-6575","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,26]]}}}