{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T20:20:20Z","timestamp":1790108420492,"version":"4.0.1"},"reference-count":32,"publisher":"S. Karger AG","issue":"1-3","license":[{"start":{"date-parts":[[2017,12,14]],"date-time":"2017-12-14T00:00:00Z","timestamp":1513209600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2017,12,14]],"date-time":"2017-12-14T00:00:00Z","timestamp":1513209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Blood Purif"],"published-print":{"date-parts":[[2018]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; We performed this study to evaluate the incidence, risk factors, microbiology, treatment, and outcome of peritonitis in pediatric Peritoneal dialysis (PD) patients at a nationwide prospective study. &lt;b&gt;&lt;i&gt;Methodology:&lt;\/i&gt;&lt;\/b&gt; Patients younger than 18 years recruited in the BRAZPD II study from 2004 to 2011, who presented their first peritonitis episode, were included in the study. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; We found 125 first episodes of peritonitis in 491 children PD patients (0.43 episodes\/patient-year). Patients free of peritonitis episode constituted 75.6% in 1 year. Culture-negative episodes were very high (59.2%) and gram-positive (GP) bacteria were the most commonly found organisms (58.8%). First-generation cephalosporin was the initial choice to cover GP (40.5%) and aminoglycosides was the most prescribed antibiotics used for gram-negative agents (27.5%). Treatment failure was 26.4%. Technique failure (TF) occurred in 12.1% and peritonitis was the main cause (65.1%). Pseudomonas (&lt;i&gt;p&lt;\/i&gt;\u00a0= 0.04) and negative cultures (&lt;i&gt;p&lt;\/i&gt;\u00a0&amp;#x3c; 0.001) were identified as predictors of TF. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Peritonitis remains a common complication of PD in children and negative cultures and pseudomonas had a negative impact on TF.<\/jats:p>","DOI":"10.1159\/000484344","type":"journal-article","created":{"date-parts":[[2017,12,14]],"date-time":"2017-12-14T22:01:41Z","timestamp":1513288901000},"page":"118-125","source":"Crossref","is-referenced-by-count":16,"title":["Peritonitis in Children on Chronic Peritoneal Dialysis: The Experience of a Large National Pediatric 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