{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T11:57:35Z","timestamp":1778155055659,"version":"3.51.4"},"reference-count":25,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney Blood Press Res"],"published-print":{"date-parts":[[2017]]},"abstract":"<b><i>Background\/Aims:<\/i><\/b> The deposition of \u03b22-microglobulin induced by reactive inflammation causing carpal tunnel syndrome (CTS) is one of the complications of dialysis-related amyloidosis in maintenance hemodialysis (MHD) patients. Air pollution levels, especially particulate matter with an aerodynamic diameter of &#x3c;2.5 mm (PM<sub>2.5<\/sub>)<sub>,<\/sub> have significantly been associated with the elevation of systemic inflammatory markers. There is no previous research on possible associations between CTS and PM<sub>2.5<\/sub>. <b><i>Methods:<\/i><\/b> This study enrolled 866 MHD patients treated at the outpatient HD centers. Senior neurologists diagnosed the presence of CTS. Air pollution levels were recorded by a network of 27 monitoring stations near or in the patients\u2019 living areas throughout Taiwan. The 12- and 24-month average concentrations of PM with an aerodynamic diameter of &#x3c;10 and &#x3c;2.5 mm (PM<sub>10<\/sub> and PM<sub>2.5<\/sub>, respectively), sulfur dioxide, nitrogen dioxide, carbon monoxide, and ozone were included. <b><i>Results:<\/i><\/b> Multivariate logistic regression analyses showed that HD duration, the normalized protein catabolic rate (nPCR), hypoalbuminemia (albumin &#x3c; 4 g\/dl), and the mean previous 12-month environmental PM<sub>2.5<\/sub> were positively associated with CTS; HD duration, nPCR, hypoalbuminemia (albumin &#x3c; 4 g\/dl), and the mean previous 24-month environmental PM<sub>2.5<\/sub> were positively associated with CTS; HD duration, hypoalbuminemia (albumin &#x3c; 4 g\/dl), and previous 12-month PM<sub>2.5<\/sub> excess days were positively associated with CTS; and HD duration, nPCR, hypoalbuminemia (albumin &#x3c; 4 g\/dl), and previous 24-month PM<sub>2.5<\/sub> excess days were positively associated with CTS. <b><i>Conclusion:<\/i><\/b> PM<sub>2.5<\/sub> levels and PM<sub>2.5<\/sub> excessing days were positively correlated with CTS.<\/jats:p>","DOI":"10.1159\/000484422","type":"journal-article","created":{"date-parts":[[2017,11,21]],"date-time":"2017-11-21T22:03:29Z","timestamp":1511301809000},"page":"827-836","source":"Crossref","is-referenced-by-count":13,"title":["Association Between Environmental Particulate Matter and Carpal Tunnel Syndrome in Patients Undergoing Hemodialysis"],"prefix":"10.1159","volume":"42","author":[{"given":"Cheng-Hao","family":"Weng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ching-Chih","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tzung-Hai","family":"Yen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Hung","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2017,11,21]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-139X.2006.00134.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijheh.2015.12.002"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1186\/s12940-015-0049-0"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1136\/oemed-2014-102800"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-015-0107-0"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.2147\/TCRM.S91475"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000000368"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0074358"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000000149"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/tox.22303"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2016.06.019"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2000.00892.x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0092710"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfu230"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2013.06.098"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1002\/tox.22287"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2016.03.033"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0152216"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.3109\/08958378.2016.1145770"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1021\/es5029876"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2015.07.020"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.3109\/08958378.2015.1040139"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0106821"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.2298\/VSP141111026S"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2016.08.012"}],"container-title":["Kidney 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Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/484422","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/484422","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:16:51Z","timestamp":1745425011000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000484422"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":25,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2018,1,4]]}},"URL":"https:\/\/doi.org\/10.1159\/000484422","archive":["Portico"],"relation":{},"ISSN":["1420-4096","1423-0143"],"issn-type":[{"value":"1420-4096","type":"print"},{"value":"1423-0143","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}