{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T03:23:57Z","timestamp":1762917837485,"version":"3.40.5"},"reference-count":30,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2017,12,5]],"date-time":"2017-12-05T00:00:00Z","timestamp":1512432000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2017,12,5]],"date-time":"2017-12-05T00:00:00Z","timestamp":1512432000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fetal Diagn Ther"],"published-print":{"date-parts":[[2019]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; A midtrimester cervical length (CL) &amp;#x3c;25 mm is associated with spontaneous preterm birth (sPTB). However, as CL \u226525 mm is not enough to exclude recurrence in high-risk patients, follow-up CL measurement later in pregnancy has been proposed. &lt;b&gt;&lt;i&gt;Objectives:&lt;\/i&gt;&lt;\/b&gt; To evaluate whether CL measurement at 26\u00b11 weeks in asymptomatic high-risk patients improves the prediction of sPTB recurrence. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; A retrospective cohort of high-risk women because of previous sPTB was analyzed. Patients with a CL \u226525 mm at 20\u00b11 weeks and subsequent CL measurement at 26\u00b11 weeks were included. The exclusion criteria were incomplete follow-up, any treatment before CL assessments, and medically indicated preterm birth. The association and predictive performance of CL at 26\u00b11 weeks for sPTB was studied. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Of 131 patients with a CL measurement at 26\u00b11 weeks, 19 and 4.6% presented sPTB before 37 and 34 weeks, respectively. The rate of sPTB before 37 weeks was higher in women with a CL &amp;#x3c;25 mm (37.5 vs. 16.5%, RR 2.3 [1.07\u20134.8], &lt;i&gt;p&lt;\/i&gt; = 0.045), although the detection rate of CL at 26\u00b11 weeks to predict sPTB before 37 weeks was 24% (95% CI 10\u201346%). The performance did not improve regardless of the selected cutoff. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; In asymptomatic high-risk patients, CL &amp;#x3c;25 mm at 26\u00b11 weeks is associated with higher risk of sPTB. However, the prediction of recurrence by CL was low and did not improve, regardless of the selected cutoff.<\/jats:p>","DOI":"10.1159\/000484522","type":"journal-article","created":{"date-parts":[[2017,12,5]],"date-time":"2017-12-05T22:01:43Z","timestamp":1512511303000},"page":"50-56","source":"Crossref","is-referenced-by-count":4,"title":["Follow-Up of Asymptomatic High-Risk Patients with Normal Cervical Length to Predict Recurrence of Preterm 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