{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T14:28:47Z","timestamp":1747232927684,"version":"3.40.5"},"reference-count":5,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T00:00:00Z","timestamp":1512518400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T00:00:00Z","timestamp":1512518400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Horm Res Paediatr"],"published-print":{"date-parts":[[2018]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; It is unclear whether Crohn\u2019s disease (CD) is associated with skeletal disproportion in adulthood. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; Height (Ht), sitting height (SHt) and leg length were studied in 44 children (male: 22), 23 adults (male: 10) with childhood-onset (CO) CD and 26 adults (male: 9) with adult-onset (AO) CD with a median (range) age of 13.7 (10, 17.3), 21.5 (18, 32) and 31.0 (22, 40) years, respectively. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Adults with CO-CD had a median Ht standard deviation score (SDS) of \u20130.9 (\u20132.3, 0.0) compared to 0.6 (\u20130.8, 1.0) in those with AO-CD (&lt;i&gt;p&lt;\/i&gt; &amp;#x3c; 0.05). Compared to a normal population, men, but not women, with CO-CD also had lower median SHt SDS at \u20131.1 (2.5, \u20130.5) (&lt;i&gt;p&lt;\/i&gt; &amp;#x3c; 0.05). The expected positive association that is normally found between leg length and SHt SDS was not evident in the adults with CO-CD. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Short stature in adults with CO-CD is more pronounced in men and may be associated with poor spinal growth.<\/jats:p>","DOI":"10.1159\/000485185","type":"journal-article","created":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T22:01:26Z","timestamp":1512597686000},"page":"132-135","source":"Crossref","is-referenced-by-count":5,"title":["Long-Term Skeletal Disproportion in Childhood-Onset Crohn\u2019s Disease"],"prefix":"10.1159","volume":"89","author":[{"given":"Avril","family":"Mason","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos","family":"Gerasimidis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jelena","family":"Iljuhhina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Laird","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joanne","family":"Munro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel\u00a0R.","family":"Gaya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard\u00a0K.","family":"Russell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0689-5549","authenticated-orcid":false,"given":"S.\u00a0Faisal","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2017,12,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2011-300771"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1159\/000329991"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1210\/er.2015-1026"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/BF01956736"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2016.08.075"}],"container-title":["Hormone Research in Paediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/485185","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/485185","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:22:52Z","timestamp":1745425372000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000485185"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,6]]},"references-count":5,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2018,2,28]]},"published-print":{"date-parts":[[2018,3,5]]}},"URL":"https:\/\/doi.org\/10.1159\/000485185","archive":["Portico"],"relation":{},"ISSN":["1663-2818","1663-2826"],"issn-type":[{"type":"print","value":"1663-2818"},{"type":"electronic","value":"1663-2826"}],"subject":[],"published":{"date-parts":[[2017,12,6]]}}}