{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T17:54:08Z","timestamp":1778003648399,"version":"3.51.4"},"reference-count":8,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2018,1,5]],"date-time":"2018-01-05T00:00:00Z","timestamp":1515110400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2018,1,5]],"date-time":"2018-01-05T00:00:00Z","timestamp":1515110400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Ophthalmol"],"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Purpose:&lt;\/i&gt;&lt;\/b&gt; To report a case of intravenous (i.v.) heroin use-associated endogenous endophthalmitis caused by &lt;i&gt;Scopulariopsis&lt;\/i&gt; fungal species, and its response to intravitreal and oral voriconazole treatments. &lt;b&gt;&lt;i&gt;Patient:&lt;\/i&gt;&lt;\/b&gt; A 21-year-old-female with chronic hepatitis C and i.v. heroin use presented with subacute decreased vision to hand motion in her left eye. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Endogenous fungal endophthalmitis caused by &lt;i&gt;Scopulariopsis&lt;\/i&gt; was confirmed by vitreous biopsy. The patient improved clinically after vitrectomy with intravitreal voriconazole and 3 weeks of oral voriconazole. The final vision was 20\/60 after 6 months. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; &lt;i&gt;Scopulariopsis&lt;\/i&gt; is a rare cause of endophthalmitis, and is often difficult to treat due to its resistance to commonly used antifungals. This case is the first report of &lt;i&gt;Scopulariopsis&lt;\/i&gt; endophthalmitis secondary to i.v. drug use.<\/jats:p>","DOI":"10.1159\/000485552","type":"journal-article","created":{"date-parts":[[2018,1,5]],"date-time":"2018-01-05T22:01:47Z","timestamp":1515189707000},"page":"43-48","source":"Crossref","is-referenced-by-count":4,"title":["Intravenous Drug Use-Associated &lt;b&gt;&lt;i&gt;Scopulariopsis&lt;\/i&gt;&lt;\/b&gt; Endophthalmitis Treated with Systemic and Intravitreal Voriconazole"],"prefix":"10.1159","volume":"9","author":[{"given":"Joseph\u00a0J.","family":"Raevis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neha","family":"Shaik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Tseng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2018,1,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1080\/13693780601103080"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200403000-00015"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/00006982-199705000-00015"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-7-87"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1179\/joc.2000.12.6.463"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2004.08.077"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.foot.2015.03.003"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000000084"}],"container-title":["Case Reports in Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/485552","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/485552","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:26:19Z","timestamp":1745425579000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000485552"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,5]]},"references-count":8,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2018,5,7]]}},"URL":"https:\/\/doi.org\/10.1159\/000485552","archive":["Portico"],"relation":{},"ISSN":["1663-2699"],"issn-type":[{"value":"1663-2699","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,5]]}}}