{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T23:23:50Z","timestamp":1783639430180,"version":"3.55.0"},"reference-count":49,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kidney Blood Press Res"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background\/Aims:&lt;\/i&gt;&lt;\/b&gt; Evidence indicates a role for dyslipidemia in the development of chronic kidney disease (CKD). However, the association of lipid abnormalities and their ratios with kidney disease using the new CKD Epidemiology Collaboration (CKD-EPI) equation is not well understood. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; This cross-sectional study included 48,054 adult subjects. CKD was defined as an estimated glomerular filtration rate &amp;#x3c;60 ml\/min\/1.73 m&lt;sup&gt;2&lt;\/sup&gt; or dipstick-positive proteinuria. Logistic regression models were used to examine the relationship between lipid variables and CKD. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; The prevalence of CKD in this study was 3.7%. When the participants exhibited higher serum triglyceride (TG), a higher TG\/high-density lipoprotein cholesterol (TG\/HDL-c) ratio or a higher non-HDL-c\/HDL-c ratio or HDL-c in a lower quartile, the prevalence of CKD tended to be higher. The multivariate adjusted odds ratios for CKD per 1 standard deviation increase in lipid level were 1.17 (1.10-1.23) for TG, 0.86 (0.79-0.93) for HDL-c, 1.21 (1.13-1.31) for the TG\/HDL-c ratio, and 1.14 (1.06-1.22) for the non-HDL-c\/HDL-c ratio. No significant association was detected between CKD and total cholesterol (TC), non-HDL-c or the low-density lipoprotein cholesterol\/HDL-c (LDL-c\/HDL-c) ratio. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; In this relatively healthy adult Chinese population, the CKD-EPI equation determined that the TG\/HDL-c and non-HDL-c\/HDL-c ratios as well as TG and HDL-c correlate with the prevalence of CKD.<\/jats:p>","DOI":"10.1159\/000485861","type":"journal-article","created":{"date-parts":[[2017,12,8]],"date-time":"2017-12-08T22:02:32Z","timestamp":1512770552000},"page":"1141-1154","source":"Crossref","is-referenced-by-count":46,"title":["Association of the TG\/HDL-C and Non-HDL-C\/HDL-C Ratios with Chronic Kidney Disease in an Adult Chinese 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