{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:27:39Z","timestamp":1745468859894,"version":"3.40.4"},"reference-count":17,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Urol Int"],"published-print":{"date-parts":[[2018]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Aims:&lt;\/i&gt;&lt;\/b&gt; To develop a nomogram with severity categories for detrusor overactivity (DO). &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; By conducting ice water tests (IWT) in 55 patients with Parkinson\u2019s disease, we identified criteria to describe characteristics of the detrusor pressure curves: (1) a gradient of \u0394&lt;i&gt;pdet&lt;\/i&gt; over \u0394t at the maximum detrusor pressure and (2) the area under the curve. In a nomogram, 10 severity categories of DO were established: 1 and 2 were assigned to group A (mild), 3 and 4 to group B (moderate) and 5\u201310 to group C (severe). &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; In the nomogram, negative IWT (20) appeared in category 1. Positive IWT (35) spread over the categories 1\u20138, 17 in group A, 11 in group B and 7 in categories 5\u201310. A relationship of incontinence episodes and nomogram category was observed. The nomogram category was reproducible in repeated IWT. Therapeutic interventions to treat DO lowered the nomogram category. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; From the relationship of detrusor pressure and time in the IWT, a nomogram with 10 severity categories of DO was developed. First observations show a relationship of nomogram category and the number of incontinence episodes, reproducibility in repeated tests and the representation of effects of therapeutic interventions to treat DO.<\/jats:p>","DOI":"10.1159\/000485901","type":"journal-article","created":{"date-parts":[[2018,1,16]],"date-time":"2018-01-16T22:01:18Z","timestamp":1516140078000},"page":"294-300","source":"Crossref","is-referenced-by-count":2,"title":["A Nomogram to Characterize the Severity of Detrusor Overactivity during the Ice Water Test: Description of the Method and Proof of Concept"],"prefix":"10.1159","volume":"100","author":[{"given":"Andr\u00e9","family":"Reitz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanja","family":"H\u00fcsch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Axel","family":"Haferkamp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2018,1,16]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1990.sp018172"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7793.1998.531bb.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)34984-4"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/00005392-200010000-00031"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)68062-7"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1994.tb07633.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1991.tb15134.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.purol.2015.05.007"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.rehab.2010.08.031"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.12.100"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410X.1997.03203.x"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2007.05.021"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1992.tb15797.x"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2490-6-31"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2014.07.022"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1993.tb16065.x"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2004.12.031"}],"container-title":["Urologia Internationalis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/485901","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/485901","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:28:45Z","timestamp":1745425725000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000485901"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":17,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2018,4,18]]},"published-print":{"date-parts":[[2018,4,26]]}},"URL":"https:\/\/doi.org\/10.1159\/000485901","archive":["Portico"],"relation":{},"ISSN":["0042-1138","1423-0399"],"issn-type":[{"type":"print","value":"0042-1138"},{"type":"electronic","value":"1423-0399"}],"subject":[],"published":{"date-parts":[[2018]]}}}