{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T13:44:27Z","timestamp":1767707067679,"version":"3.40.4"},"reference-count":7,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2018,10,24]],"date-time":"2018-10-24T00:00:00Z","timestamp":1540339200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2018,10,24]],"date-time":"2018-10-24T00:00:00Z","timestamp":1540339200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Dermatol"],"abstract":"<jats:p>Proctosedyl\u00ae and Proctomyxin\u00ae are two commonly prescribed hemorrhoid therapies. Their topical application to the perianal region may be complicated by a local allergic contact dermatitis and subsequent autoeczematization reaction. We present three cases of an autoeczematization (ID) reaction to varying topical allergens found in Proctosedyl\u00ae\/Proctomyxin\u00ae. It is our recommendation that physician and patient education, avoidance of allergens (or cross-reactants), and appropriate choice of topical corticosteroid is important in preventing and avoiding flares.<\/jats:p>","DOI":"10.1159\/000486475","type":"journal-article","created":{"date-parts":[[2018,10,24]],"date-time":"2018-10-24T21:02:38Z","timestamp":1540414958000},"page":"238-246","source":"Crossref","is-referenced-by-count":4,"title":["Allergic Contact Dermatitis and Autoeczematization to Proctosedyl\u00ae Cream and Proctomyxin\u00ae Cream"],"prefix":"10.1159","volume":"10","author":[{"given":"J.D.\u00a0Matthew","family":"Hughes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melanie\u00a0D.","family":"Pratt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2018,10,24]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2003.11.048"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-011-0846-8"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2005.00683.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2009.02082.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700174"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-0960.2001.00493.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000097"}],"container-title":["Case Reports in Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/486475","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/486475","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:34:21Z","timestamp":1745426061000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000486475"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,24]]},"references-count":7,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2019,1,7]]}},"URL":"https:\/\/doi.org\/10.1159\/000486475","archive":["Portico"],"relation":{},"ISSN":["1662-6567"],"issn-type":[{"type":"electronic","value":"1662-6567"}],"subject":[],"published":{"date-parts":[[2018,10,24]]}}}