{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:27:24Z","timestamp":1745468844307,"version":"3.40.4"},"reference-count":18,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Cytologica"],"published-print":{"date-parts":[[2018]]},"abstract":"<b><i>Objective:<\/i><\/b> The aim of this work was to evaluate 100% rapid review (100% RR) as a useful tool to detect false negative (FN) results.<b><i> Study Design:<\/i><\/b> A sample of 8,677 swabs was investigated; the unsatisfactory and negative results were referred to 100% RR, concordant results were taken as the final diagnosis, while the discordant results were debated in a consensus meeting to reach a conclusion. The positive results were examined by 2 cytologists. The data were entered into SAS statistical software, and the agreement of the 100% RR results with the final diagnosis was tested with the weighted kappa statistic. <b><i>Results:<\/i><\/b> There was a significant increase in unsatisfactory results from 348 to 1,927, and of positive results from 174 to 349. On the other hand, there was a substantial decrease in negative results from 8,155 to 6,401. Assessing the relative risk of FN results in smears that were not referred to quality control (100% RR) revealed the following results: atypical squamous cells of undetermined significance (ASC-US), 2.93; low-grade squamous intraepithelial lesion (LSIL), 2.72; high-grade squamous intraepithelial lesion\/atypical squamous cells \u2013 cannot exclude HSIL (HSIL\/ASC-H), 2.25. Evaluating by age group, a higher risk for LSIL (4.90) and ASC-US (3.85) was observed in patients aged under 25 years, whereas patients between 25 and 64 years and those over 64 years presented a higher risk for HSIL and ASC-H: 2.46 and 2.75, respectively. <b><i>Conclusion:<\/i><\/b> 100% RR is an effective screening tool for FN results in countries where molecular tests for DNA-HPV and prophylactic vaccines are not available in cervical cancer screening programs.<\/jats:p>","DOI":"10.1159\/000488872","type":"journal-article","created":{"date-parts":[[2018,5,22]],"date-time":"2018-05-22T21:01:22Z","timestamp":1527022882000},"page":"209-214","source":"Crossref","is-referenced-by-count":1,"title":["Does 100% Rapid Review Improve Cervical Cancer Screening?"],"prefix":"10.1159","volume":"62","author":[{"given":"Jos\u00e9","family":"Queiroz\u00a0Filho","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9","family":"Eleut\u00e9rio,\u00a0Jr.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo","family":"Ney\u00a0Cobucci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janaina\u00a0Cristiana","family":"de\u00a0Oliveira\u00a0Crispim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo\u00a0C\u00e9sar","family":"Giraldo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana\u00a0Katherine","family":"Gon\u00e7alves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2018,5,22]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.30901"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ram.2017.06.004"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1186\/s12905-016-0342-2"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.canep.2016.08.014"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1055\/s-0036-1582399"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-72032008001100005"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1590\/S1679-45082012000100018"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1159\/000441515]"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-72032006000800007"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2303.2010.00776.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1159\/000368041"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.20190"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1159\/000475833"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002\/dc.23783"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1002\/dc.22904"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1186\/s12907-017-0058-8"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1159\/000325196"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.4103\/0377-4929.56134"}],"container-title":["Acta Cytologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/488872","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/488872","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:23:32Z","timestamp":1745425412000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000488872"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":18,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2018,6,7]]},"published-print":{"date-parts":[[2018,6,18]]}},"URL":"https:\/\/doi.org\/10.1159\/000488872","archive":["Portico"],"relation":{},"ISSN":["0001-5547","1938-2650"],"issn-type":[{"type":"print","value":"0001-5547"},{"type":"electronic","value":"1938-2650"}],"subject":[],"published":{"date-parts":[[2018]]}}}