{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:55:40Z","timestamp":1773363340358,"version":"3.50.1"},"reference-count":16,"publisher":"S. Karger AG","issue":"1-2","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2018]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; The Actinic Keratosis Quality of Life Questionnaire (AKQoL) is a disease-specific instrument to measure the impact of actinic keratosis (AK) on patients\u2019 lives. &lt;b&gt;&lt;i&gt;Objective:&lt;\/i&gt;&lt;\/b&gt; To validate and test the psychometric properties of the AKQoL translated into the Dutch language (AKQoL-NL). &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; All new patients \u226550 years of age with untreated AK in a university medical center and a general hospital between August 2014 and August 2015 were eligible. The AKQoL was obtained and repeated after 2 weeks. The feasibility was tested by missing responses and response distribution. The internal consistency reliability of each domain was investigated with the Cronbach alpha, and test-retest reliability and validity with the Spearman correlation coefficient. AKQoL scores were compared to the Skindex-17 for convergent validity and to the Groningen Frailty Indicator scores for divergent validity. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; A total of 153 of 190 eligible patients consented to participate. Feasibility analysis showed that none of the items missed \u226510% of responses but 5 of the 9 items showed floor effect. The AKQoL subscales showed a moderate internal consistency (Cronbach \u03b1 = 0.235\u20130.468) and an excellent test-retest reliability (interclass correlation coefficient = 0.997\u20131). The AKQoL correlated poorly with the symptom component and moderately with the psychosocial component of the Skindex-17 (\u03c1 = \u20130.015 to 0.346 and 0.324 to 0.501, respectively), which is less than expected. The AKQoL scored poorly in both of the Groningen Frailty Indicator (GFI) components (\u03c1 = \u20130.97 to 0.12 and 0.185 to 0.276, respectively), as expected. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; The AKQoL-NL is a feasible, moderately valid, and moderately reliable health-related quality of life questionnaire.<\/jats:p>","DOI":"10.1159\/000489118","type":"journal-article","created":{"date-parts":[[2018,6,15]],"date-time":"2018-06-15T21:01:33Z","timestamp":1529096493000},"page":"60-65","source":"Crossref","is-referenced-by-count":5,"title":["Validity and Reliability of the Dutch Adaptation of the Actinic Keratosis Quality of Life Questionnaire (AKQoL)"],"prefix":"10.1159","volume":"234","author":[{"given":"Kelly","family":"Vis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6163-9164","authenticated-orcid":false,"given":"Rick","family":"Waalboer-Spuij","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dyon\u00a0G.C.T.M.","family":"Snels","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Loes\u00a0M.","family":"Hollestein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2018,6,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2000.103342"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2000.03541.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.142.6.722"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5701142"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700212"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12036"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2016.03.003"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14127"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2013.134"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2011.483"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12629"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(98)00082-1"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2012.244"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2012.04.007"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1186\/s12955-015-0295-4"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12420"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/489118","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/489118","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:26:22Z","timestamp":1745425582000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000489118"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":16,"journal-issue":{"issue":"1-2","published-online":{"date-parts":[[2018,7,19]]},"published-print":{"date-parts":[[2018,7,26]]}},"URL":"https:\/\/doi.org\/10.1159\/000489118","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.6541265","asserted-by":"subject"}]},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018]]}}}