{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:27:36Z","timestamp":1745468856363,"version":"3.40.4"},"reference-count":0,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respiration"],"published-print":{"date-parts":[[2018]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; The SERVE-HF study has raised questions concerning the higher mortality under adaptive servoventilation. The ventilatory mode was discussed as a possible aggravating factor. &lt;b&gt;&lt;i&gt;Objectives:&lt;\/i&gt;&lt;\/b&gt; We wondered if the data recorded by the adaptive servo-ventilation (ASV)-devices in heart failure patients with CSA-CSR \u00b1 OSA are different in terms of respiratory parameters and therapeutic pressures compared to patients with CPAP-resistant\/emergent-CSA with normal BNP\/NT-pro-BNP. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; Patients were included, if ASV had normalized respiratory disturbance index in the first night of application and after at least 6 weeks. ASV-device data were analyzed in terms of respiratory rate (RR), min ventilation (MV), endexpiratory (EEP), peak inspiratory pressure (Ppeak) and median pressure. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Compared to CPAP-resistant\/emergent-CSA with normal BNP\/NT-pro-BNP (&lt;i&gt;n&lt;\/i&gt; = 25), CSA-CSR- (&lt;i&gt;n&lt;\/i&gt; = 13) CSA-CSR+OSA-patients (&lt;i&gt;n&lt;\/i&gt; = 32) with elevated BNP\/NT-pro-BNP had higher RR (&lt;i&gt;p&lt;\/i&gt; &amp;#x3c; 0.01) in the first night of ASV therapy and during follow-up (15.3 \u00b1 1.3 vs. 17.3 \u00b1 2.4\/min) with similar MV (6.5 \u00b1 1.3 vs. 6.6 \u00b1 1.3 L), resulting in significantly lower tidal volumes. EEP (5.6 \u00b1 1.1 vs. 5.5 \u00b1 1.1 hPa), Pmedian and Ppeak (9.8 \u00b1 1.5 vs. 9.7 \u00b1 1.2 hPa) were comparable. Ventilatory parameters were not different between LVEF &amp;#x3c; 40, 40\u201349, and \u226550%, neither within the whole group nor the group of CSA-CSR \u00b1 OSA and heart failure. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Patients with heart failure and CSA-CSR \u00b1 OSA have higher RRs but similar MV under ASV-therapy than patients with CSA and normal BNP. This indicates higher dead space ventilation. EF was not found to have an influence on the ventilatory parameters.<\/jats:p>","DOI":"10.1159\/000489228","type":"journal-article","created":{"date-parts":[[2018,7,4]],"date-time":"2018-07-04T21:01:24Z","timestamp":1530738084000},"page":"240-248","source":"Crossref","is-referenced-by-count":1,"title":["Ventilation Parameters under Adaptive Servo Ventilation: A Comparison on Behalf of CSA-Pattern, BNP\/NT-pro-BNP, and Ejection Fraction"],"prefix":"10.1159","volume":"96","author":[{"given":"Michael","family":"Westhoff","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patric","family":"Litterst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2018,6,25]]},"container-title":["Respiration"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/489228","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/489228","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:27:22Z","timestamp":1745425642000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000489228"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2018,10,10]]},"published-print":{"date-parts":[[2018,10,17]]}},"URL":"https:\/\/doi.org\/10.1159\/000489228","archive":["Portico"],"relation":{},"ISSN":["0025-7931","1423-0356"],"issn-type":[{"type":"print","value":"0025-7931"},{"type":"electronic","value":"1423-0356"}],"subject":[],"published":{"date-parts":[[2018]]}}}