{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T04:28:38Z","timestamp":1790310518400,"version":"4.1.0"},"reference-count":9,"publisher":"S. Karger AG","issue":"3-4","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Allergy Immunol"],"published-print":{"date-parts":[[2018]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Introduction:&lt;\/i&gt;&lt;\/b&gt; Celiac disease and wheat allergy (WA) are infrequent diseases in the general population, and a combination of the 2 is particularly rare. Celiac disease occurs in around 1% of the general population and WA in around 1% of all children. &lt;b&gt;&lt;i&gt;Case Report:&lt;\/i&gt;&lt;\/b&gt; We report 2 patients with celiac disease and a gluten-free diet who developed WA consistent in anaphylaxis and an eyelid angioedema, respectively, through accidental wheat exposure. A serum study and an intestinal biopsy confirmed celiac disease. Both patients were studied with a skin prick test and serum-specific IgE, with a diagnosis of WA. &lt;b&gt;&lt;i&gt;Discussion:&lt;\/i&gt;&lt;\/b&gt; In patients with celiac disease, the trace amounts of cereals present in gluten-free food could act as a sensitization factor, and probably patients with persistent symptoms (despite a gluten-free diet) are experiencing WA symptoms rather than celiac disease symptoms. The number of patients diagnosed with celiac disease has increased in the recent decades: the association between celiac disease and WA, exceedingly rare to date, could increase as well, prompting special attention to the possibility of inadvertent intake of cereals.<\/jats:p>","DOI":"10.1159\/000489305","type":"journal-article","created":{"date-parts":[[2018,5,30]],"date-time":"2018-05-30T21:01:22Z","timestamp":1527714082000},"page":"280-282","source":"Crossref","is-referenced-by-count":9,"title":["Celiac Disease and Wheat Allergy: A Growing Association?"],"prefix":"10.1159","volume":"176","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6857-7477","authenticated-orcid":false,"given":"Sarah","family":"Micozzi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonsoles","family":"Infante","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Fuentes-Aparicio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"\u00c1lvarez-Perea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lydia","family":"Zapatero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2018,5,30]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i23.7110"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2008.03101.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1186\/1710-1492-10-56"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/pai.12487"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2011-301346"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2010.02346.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1159\/000102609"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2009.01955.x"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/apt.12859"}],"container-title":["International Archives of Allergy and Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/489305","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/489305","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:28:19Z","timestamp":1745425699000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000489305"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":9,"journal-issue":{"issue":"3-4","published-online":{"date-parts":[[2018,7,11]]},"published-print":{"date-parts":[[2018,7,19]]}},"URL":"https:\/\/doi.org\/10.1159\/000489305","archive":["Portico"],"relation":{},"ISSN":["1018-2438","1423-0097"],"issn-type":[{"value":"1018-2438","type":"print"},{"value":"1423-0097","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018]]}}}