{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T21:03:42Z","timestamp":1762808622206,"version":"3.40.4"},"reference-count":11,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2018,5,31]],"date-time":"2018-05-31T00:00:00Z","timestamp":1527724800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2018,5,31]],"date-time":"2018-05-31T00:00:00Z","timestamp":1527724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Oncol"],"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Introduction:&lt;\/i&gt;&lt;\/b&gt; The coexistence of chronic lymphocytic leukemia\/small lymphocytic lymphoma (CLL\/SLL) with different gynecologic neoplasms is a rare phenomenon. Here, we report a case of simultaneously developed CLL\/SLL with endometrioid-type uterine cancer. &lt;b&gt;&lt;i&gt;Case Report:&lt;\/i&gt;&lt;\/b&gt; A 58-year-old woman was admitted to the 2nd Department of Gynecology, Lublin Medical University, Lublin, Poland, in June 2017, where the uterine cancer was diagnosed. After the surgery, pathological examination revealed a uterine moderately differentiated adenocarcinoma of endometrioid subtype (subtype I according to Bokhman) deeply infiltrating the myometrium as well as the uterine cervix. Surprisingly, CLL\/SLL was subsequently diagnosed in all removed pelvic as well as para-aortic lymph nodes. Immunohistochemical analysis showed CD45 (++), CD20 (+), CD3 (\u2013\/+), CD19 (+), CD23 (+), CD5 (+), and CD34 (+). Proliferative activity, assessed by MIB-1 proliferative index immunostaining, reached 18%. The patient was admitted to radiotherapy and chemotherapy at the Oncology Hospital, Lublin, Poland, and is still on follow-up. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; The coexistence of CLL\/SLL with various gynecological malignancies, especially primary human endometrial cancer, is a rare entity. The detection of both tumors simultaneously, in general, is accidental, and the management should not be different from the situation in which malignancy appears de novo.<\/jats:p>","DOI":"10.1159\/000489662","type":"journal-article","created":{"date-parts":[[2018,5,31]],"date-time":"2018-05-31T21:04:02Z","timestamp":1527800642000},"page":"347-352","source":"Crossref","is-referenced-by-count":5,"title":["An Unusual Coexistence of Chronic Lymphocytic Leukemia\/Small Lymphocytic Lymphoma with Endometrioid-Type Endometrial Cancer in a 58-Year-Old Woman: A Case Study with Literature Review"],"prefix":"10.1159","volume":"11","author":[{"given":"Dominik","family":"D\u0142uski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorota","family":"Lewkowicz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo\u017cena","family":"Leszczy\u0144ska-Gorzelak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bogdan","family":"Obrzut","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomasz","family":"Rechberger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrzej","family":"Semczuk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2018,5,31]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1177\/0036933015619590"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-06-093906"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1186\/s40248-017-0107-2"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.17.5398"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.22672"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s11864-004-0013-7"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1080\/10428190400007524"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1054\/bjoc.2001.1998"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.04.2200"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.4274\/tjh.2012.0169"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.clbc.2015.02.001"}],"container-title":["Case Reports in Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/489662","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/489662","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:31:42Z","timestamp":1745425902000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000489662"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,31]]},"references-count":11,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2018,12,20]]},"published-print":{"date-parts":[[2018,8,31]]}},"URL":"https:\/\/doi.org\/10.1159\/000489662","archive":["Portico"],"relation":{},"ISSN":["1662-6575"],"issn-type":[{"type":"electronic","value":"1662-6575"}],"subject":[],"published":{"date-parts":[[2018,5,31]]}}}