{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T21:55:50Z","timestamp":1759010150215,"version":"3.40.4"},"reference-count":8,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2018,7,18]],"date-time":"2018-07-18T00:00:00Z","timestamp":1531872000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2018,7,18]],"date-time":"2018-07-18T00:00:00Z","timestamp":1531872000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Neurol"],"abstract":"<jats:p>We report a rare case of meningitis due to a combination of &lt;i&gt;Streptococcus mitis&lt;\/i&gt; and &lt;i&gt;Neisseria subflava&lt;\/i&gt;. An 80-year-old female had a 4-year history of type II diabetes mellitus (DM) and an 11-year history of rheumatoid arthritis, which was treated with prednisolone, tacrolimus, and methotrexate. One month after the removal of a dental implant, she complained of a disturbance of consciousness and suffered a convulsion. A cerebrospinal fluid culture was found to be positive for both &lt;i&gt;S. mitis&lt;\/i&gt; and &lt;i&gt;N. subflava&lt;\/i&gt;. After 14 days of antibiotic treatment with 4 g\/day ceftriaxone, her stiff neck, somnolence, and laboratory data greatly improved, and she was successfully discharged at 27 days after admission. Although both &lt;i&gt;S. mitis&lt;\/i&gt; and &lt;i&gt;N. subflava&lt;\/i&gt; are generally considered to be benign bacteria, they can cause meningitis in patients with the following risk factors: older age, on immunosuppressive treatment, DM, or dental treatment.<\/jats:p>","DOI":"10.1159\/000490695","type":"journal-article","created":{"date-parts":[[2018,7,18]],"date-time":"2018-07-18T21:22:49Z","timestamp":1531948969000},"page":"177-180","source":"Crossref","is-referenced-by-count":5,"title":["Meningitis due to a Combination of &lt;b&gt;&lt;i&gt;Streptococcus mitis&lt;\/i&gt;&lt;\/b&gt; and &lt;b&gt;&lt;i&gt;Neisseria subflava&lt;\/i&gt;&lt;\/b&gt;: A Case Report"],"prefix":"10.1159","volume":"10","author":[{"given":"Kana","family":"Fukumoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiro","family":"Manabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunya","family":"Fujiwara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshio","family":"Omote","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisashi","family":"Narai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haruto","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Saito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Abe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2018,7,18]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/00043426-199701000-00013"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1966.03100100073019"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.1975.16.1.44"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1086\/313700"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2008.01.003"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1996.00440140204024"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.4236\/crcm.2014.37088"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3201\/eid2006.131117"}],"container-title":["Case Reports in Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/490695","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/490695","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:41:26Z","timestamp":1745426486000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000490695"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,18]]},"references-count":8,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2018,10,4]]}},"URL":"https:\/\/doi.org\/10.1159\/000490695","archive":["Portico"],"relation":{},"ISSN":["1662-680X"],"issn-type":[{"type":"electronic","value":"1662-680X"}],"subject":[],"published":{"date-parts":[[2018,7,18]]}}}