{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:40:32Z","timestamp":1790700032443,"version":"4.1.0"},"reference-count":0,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2018,10,26]],"date-time":"2018-10-26T00:00:00Z","timestamp":1540512000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2018,10,26]],"date-time":"2018-10-26T00:00:00Z","timestamp":1540512000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gerontology"],"published-print":{"date-parts":[[2019]]},"abstract":"<b><i>Objectives:<\/i><\/b> To directly compare the effects of agility exergaming (EXE) and stationary cycling (CYC) exercise training on Parkinson\u2019s disease (PD) patients\u2019 mobility and clinical symptoms. <b><i>Design:<\/i><\/b> Randomized clinical trial. <b><i>Setting:<\/i><\/b> Outpatient physiotherapy clinic in a hospital. <b><i>Participants:<\/i><\/b> Seventy-four stage 2\u20133, nondemented PD patients were included in this study. <b><i>Intervention:<\/i><\/b> The groups were as follows: EXE (<i>n<\/i> = 25), CYC (<i>n<\/i> = 25), and a wait-listed control group (CON; <i>n<\/i> = 24). The EXE and CYC groups exercised 5\u00d7\/week for 5 weeks, matched at 80% of the age-predicted maximal heart rate. <b><i>Main Outcomes:<\/i><\/b> The primary outcome was the Movement Disorders Society Unified Parkinson\u2019s Disease Rating Scale (UPDRS-II) score. Secondary outcomes were Parkinson\u2019s Disease Quastionnaire-39 (PDQ-39), the Beck Depression Inventory (BDI), the Schwab and England Activities of Daily Living (SE-ADL) scale, Euro-Quality of Life-5 Dimensions (EQ-5D) questionnaire, the Berg Balance Scale (BBS), the Balance Evaluation Systems Test (BESTest), the Tinetti Assessment Tool (TAT), the Dynamic Gait Index, the 6-min walk test (6MWT), and standing posturography. <b><i>Results:<\/i><\/b> After treatment, UPDRS-II scores improved (mean change: EXE, \u20134.5 points; CYC, \u20133.2 points). The results for the other outcomes (EXE and CYC, respectively) were: PDQ, 13 and 17%; BDI, \u20132.5 and \u20132.1 points; 6MWT, 129.6 and 141.6 m; and EQ-5D, 12 and 9% (all <i>p<\/i> &#x3c; 0.05, but there was no difference between groups). EXE vs. CYC resulted in improved SE-ADL (8.4 and 4.0 points, effect size [ES]: 0.12), BBS (8.8 and 4.2 points, ES: 0.44), and 2 measures of posturography (ES: 0.11 and 0.21) (<i>p<\/i> &#x3c; 0.05). BESTtest, TAT, the Dynamic Gait Index, and 4 out of 6 posturography measures did not change (<i>p<\/i> &#x3e; 0.05). <b><i>Conclusion:<\/i><\/b> Two highly different exercise programs resulted in similar improvement of most motor and clinical symptoms in PD patients.<\/jats:p>","DOI":"10.1159\/000493127","type":"journal-article","created":{"date-parts":[[2018,10,26]],"date-time":"2018-10-26T21:01:30Z","timestamp":1540587690000},"page":"120-127","source":"Crossref","is-referenced-by-count":94,"title":["Vastly Different Exercise Programs Similarly Improve Parkinsonian Symptoms: A Randomized Clinical Trial"],"prefix":"10.1159","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7607-6739","authenticated-orcid":false,"given":"J\u00f3zsef","family":"Toll\u00e1r","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferenc","family":"Nagy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tibor","family":"Hortob\u00e1gyi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2018,10,26]]},"container-title":["Gerontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/493127","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/493127","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:48:35Z","timestamp":1745426915000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000493127"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,26]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2019,3,20]]},"published-print":{"date-parts":[[2019,3,26]]}},"URL":"https:\/\/doi.org\/10.1159\/000493127","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.7257302","asserted-by":"subject"}]},"ISSN":["0304-324X","1423-0003"],"issn-type":[{"value":"0304-324X","type":"print"},{"value":"1423-0003","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,26]]}}}