{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T00:51:08Z","timestamp":1745542268285,"version":"3.40.4"},"reference-count":15,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2018,9,27]],"date-time":"2018-09-27T00:00:00Z","timestamp":1538006400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2018,9,27]],"date-time":"2018-09-27T00:00:00Z","timestamp":1538006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Nephrol Dial"],"abstract":"<jats:p>Bile cast nephropathy (BCN) is seen in patients who have acute kidney injury and severe hyperbilirubinemia due to a wide range of hepatobiliary system diseases. Findings seen by renal biopsy include acute tubular injury with necrotic and sloughed epithelial cells, yellow-green pigment within tubular epithelial cells, and pigmented granular casts. Hall\u2019s special stain for bile turns these casts green. In recent years, BCN has been described in a small number of case reports and clinical studies primarily in the setting of severe liver dysfunction. We present 2 diverse cases of BCN. The first involves an adult with hepatorenal syndrome secondary to alcoholic steatohepatitis and early cirrhosis. Second, we describe the first reported case of BCN in a child with fulminant hepatic failure due to Wilson\u2019s disease. Our cases expand the spectrum of causative diseases, and they provide further evidence that BCN is a distinct pathologic entity which may be found in both adult and pediatric patients with a variety of severe liver diseases.<\/jats:p>","DOI":"10.1159\/000493231","type":"journal-article","created":{"date-parts":[[2018,9,27]],"date-time":"2018-09-27T21:02:34Z","timestamp":1538082154000},"page":"207-215","source":"Crossref","is-referenced-by-count":9,"title":["Bile Cast Nephropathy: A Pathologic Finding with Manifold Causes Displayed in an Adult with Alcoholic Steatohepatitis and in a Child with Wilson\u2019s Disease"],"prefix":"10.1159","volume":"8","author":[{"given":"Jose","family":"Torrealba","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathan\u00a0T.","family":"Sweed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Burguete","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allen\u00a0R.","family":"Hendricks","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2018,9,27]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0809139"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/hep.26599"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.01340406"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.14218\/JCTH.2016.00063"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2013.78"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1093\/ckj\/sfw042"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2016.08.023"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v22.i27.6328"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.5414\/CN108696"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2014.05.010"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1093\/ndtplus\/sfr038"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2004.03.147"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2015.09.013"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2017.08.028"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2017.02.019"}],"container-title":["Case Reports in Nephrology and Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/493231","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/493231","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:50:05Z","timestamp":1745427005000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000493231"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,27]]},"references-count":15,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2018,12,21]]}},"URL":"https:\/\/doi.org\/10.1159\/000493231","archive":["Portico"],"relation":{},"ISSN":["2296-9705"],"issn-type":[{"type":"electronic","value":"2296-9705"}],"subject":[],"published":{"date-parts":[[2018,9,27]]}}}