{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T14:21:10Z","timestamp":1783693270714,"version":"3.55.0"},"reference-count":11,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2018,11,14]],"date-time":"2018-11-14T00:00:00Z","timestamp":1542153600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2018,11,14]],"date-time":"2018-11-14T00:00:00Z","timestamp":1542153600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Ophthalmol"],"abstract":"<jats:p>We report a severe case of diffuse lamellar keratitis (DLK) following femtosecond laser-assisted in situ keratomileusis (femto-LASIK). A 25-year-old man was submitted to 150 kHz iFS\u00ae IntraLase-assisted LASIK in both eyes for compound myopic astigmatism. The day after surgery, clinical examination showed a diffuse whitish granular cell reaction particularly in the right eye. High-dose dexamethasone eyedrops with topical antibiotic and artificial tears were prescribed. Five days after surgery, a central corneal opacity with convergent striae was detected at biomicroscopy. The suspicion of DLK was confirmed. Additional therapy based on hyperosmolar ophthalmological solution, oral doxycycline, and topical 10% sodium citrate was prescribed. Treatment was continued and tapered for over 3 months. Improvement in corneal transparency were obtained 2 weeks after the systemic therapy had been started. Uncorrected visual acuity improved from 20\/32 to 20\/20 at 1-year follow-up. DLK represents an infrequent complication after femto-LASIK. It should resolve without sequelae if promptly diagnosed and treated, without necessity of corneal flap lifting.<\/jats:p>","DOI":"10.1159\/000493338","type":"journal-article","created":{"date-parts":[[2018,11,14]],"date-time":"2018-11-14T22:01:40Z","timestamp":1542232900000},"page":"457-464","source":"Crossref","is-referenced-by-count":8,"title":["Diagnosis, Clinical Trend, and Treatment of Diffuse Lamellar Keratitis after Femtosecond Laser-Assisted in situ Keratomileusis: A Case Report"],"prefix":"10.1159","volume":"9","author":[{"given":"Angelo","family":"Balestrazzi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Balestrazzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria\u00a0Ilaria","family":"Giannico","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Michieletto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilio","family":"Balestrazzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2018,11,14]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(98)99044-3"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcjo.2016.07.004"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(02)01835-7"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(98)80347-7"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2014.05.041"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S47341"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2010.09.003"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(00)00468-5"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(01)00958-0"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097\/01.ico.0000127477.14304.de"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2005.12.037"}],"container-title":["Case Reports in Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/493338","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/493338","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:50:37Z","timestamp":1745427037000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000493338"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,14]]},"references-count":11,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2019,1,7]]}},"URL":"https:\/\/doi.org\/10.1159\/000493338","archive":["Portico"],"relation":{},"ISSN":["1663-2699"],"issn-type":[{"value":"1663-2699","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,14]]}}}