{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T07:27:59Z","timestamp":1791530879469,"version":"4.3.4"},"reference-count":29,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Obes Facts"],"published-print":{"date-parts":[[2019]]},"abstract":"<b><i>Objectives:<\/i><\/b> The frequency of postprandial hypoglycaemia after different operative procedures of bariatric surgery (BS) is unknown, although this complication is potentially dangerous. Predictors and severity of hypoglycaemia after Roux-en-Y gastric bypass (RYGB), sleeve gastrectomy, and gastric banding were investigated in a large prospective study. <b><i>Methods:<\/i><\/b> This study was performed at an excellence centre for BS at a tertiary care institution. Data of 333 patients (mean BMI: 44.9 \u00b1 9.6 kg\/m<sup>2<\/sup>; mean age: 40 \u00b1 10 years; 80.7% women) were analysed in a prospective study with a 2-year observation period after BS. All patients underwent a 2-hour oral glucose tolerance test (OGTT) with measurements of blood glucose (BG) and insulin. For the purpose of this study, hypoglycaemia was defined as a post-challenge BG &#x3c;2.8 mmol\/L during the OGTT. <b><i>Results:<\/i><\/b> 72 (25.6%) of 281 patients showed post-challenge hypoglycaemia after surgery. Hypoglycaemia was different after various procedures: 32.6% of patients after RYGB, 22.6% after sleeve gastrectomy, but only 2.3% after gastric banding had hypoglycaemia. In the whole group, patients with hypoglycaemia had lost more weight (<i>p<\/i> = 0.013), had a slightly greater decrease in BMI (<i>p<\/i> = 0.037), a greater change in 2-hour post-challenge BG (<i>p<\/i> = 0.001), and a smaller change in 1-hour post-challenge insulin (<i>p<\/i> = 0.004) compared to patients without hypoglycaemia. <b><i>Conclusion:<\/i><\/b> This prospective study shows a higher prevalence of severe hypoglycaemia (25.6%) after BS than anticipated from retrospective registers. A systematic evaluation of glucose and insulin levels by OGTT 2 years post-surgery may help to identify patients at increased risk for symptomatic and asymptomatic hypoglycaemia.<\/jats:p>","DOI":"10.1159\/000493735","type":"journal-article","created":{"date-parts":[[2019,6,24]],"date-time":"2019-06-24T22:17:31Z","timestamp":1561414651000},"page":"397-406","source":"Crossref","is-referenced-by-count":33,"title":["Frequency of Hypoglycaemia after Different Bariatric Surgical 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