{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T20:47:09Z","timestamp":1761598029418,"version":"3.40.4"},"reference-count":7,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Haematol"],"published-print":{"date-parts":[[2019]]},"abstract":"<jats:p>BK polyomavirus-associated haemorrhagic cystitis (BKHC) is a complication after allogeneic stem cell transplantation, which can occur in 5\u201360% of the cases. BK viruria alone can also occur in up to 100%. BKHC can lead to severe morbidity in stem cell-transplanted patients, but data about this disease is limited. Consequently, we conducted a prospective unicentric non-interventional trial on BKHC as well as BK viruria after first adult allogeneic stem cell transplantation with a follow-up time of 1 year after inpatient treatment. Between November 2013 and December 2015, we were able to include 40 adult patients with a mean age of 52.8 years. Twenty-seven (67.5%) of these patients were male and 13 (32.5%) were female. Acute myeloid leukaemia was the most frequent underlying disease (&lt;i&gt;n&lt;\/i&gt; = 15; 37.5%). Only 1 patient developed BKHC during inpatient treatment (&lt;i&gt;n&lt;\/i&gt; = 1; 2.5%), but BK viruria was frequent (&lt;i&gt;n&lt;\/i&gt; = 11; 27.5%) during inpatient treatment as well as in the follow-up time (&lt;i&gt;n&lt;\/i&gt; = 14; 35%). Interestingly, BK viruria was significantly associated with mucositis (&lt;i&gt;p&lt;\/i&gt; = 0.038) and number of transfused platelet concentrates (&lt;i&gt;p&lt;\/i&gt; = 0.001). This unexpected association will be discussed and needs further investigation.<\/jats:p>","DOI":"10.1159\/000494748","type":"journal-article","created":{"date-parts":[[2019,1,3]],"date-time":"2019-01-03T22:02:57Z","timestamp":1546552977000},"page":"65-67","source":"Crossref","is-referenced-by-count":4,"title":["Is BK Virus-Associated Cystitis a Generalized Epithelial Disease?"],"prefix":"10.1159","volume":"141","author":[{"given":"Laila","family":"Schneidewind","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Neumann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathrin","family":"Zimmermann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Weigel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian\u00a0Andreas","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Kr\u00fcger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2019,1,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/0090-4295(94)90079-5"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.medmal.2012.04.011"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.11.5394-5396.2004"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1159\/000445124"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.13635"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2013.235"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-016-0872-4"}],"container-title":["Acta Haematologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/494748","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/494748","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:07:25Z","timestamp":1745428045000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000494748"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":7,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2019,2,27]]}},"URL":"https:\/\/doi.org\/10.1159\/000494748","archive":["Portico"],"relation":{},"ISSN":["0001-5792","1421-9662"],"issn-type":[{"type":"print","value":"0001-5792"},{"type":"electronic","value":"1421-9662"}],"subject":[],"published":{"date-parts":[[2019]]}}}