{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T21:21:20Z","timestamp":1772054480674,"version":"3.50.1"},"reference-count":23,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2018,12,13]],"date-time":"2018-12-13T00:00:00Z","timestamp":1544659200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2018,12,13]],"date-time":"2018-12-13T00:00:00Z","timestamp":1544659200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ocul Oncol Pathol"],"published-print":{"date-parts":[[2019]]},"abstract":"<b><i>Background\/Aims:<\/i><\/b> To evaluate teleophthalmological assessment of choroidal and iris nevi (tele-oncology) compared to traditional in-person clinical evaluation for detection of either axial or basal growth. <b><i>Methods:<\/i><\/b> This is a validation study. All 97 eyes of 99 patients were evaluated with an in-person ocular oncology visit utilizing standard testing, and subsequently had a tele-oncology evaluation with the standardized tests. The tele-oncology reviewer was blinded to the in-person examination findings. The primary study outcome was detection of nevus growth on tele-oncology compared to in-person clinical examination. <b><i>Results:<\/i><\/b> Patients had a mean age of 61 years and the majority had nevi located in the choroid (<i>n<\/i> = 87; 88%). The most common diagnosis was a low-risk nevus (<i>n<\/i> = 38; 44%). By tele-oncology assessment, 11 eyes showed growth. Ten of these patients had growth confirmed on in-person clinical examination. Resultantly, tele-oncology assessment of choroidal and iris nevi growth had a sensitivity of 100%, specificity of 99%, positive predictive value (PPV) of 91%, and negative predictive value (NPV) of 100%. <b><i>Conclusions:<\/i><\/b> The results of this study suggest that tele-oncology is a safe platform for monitoring choroidal and iris nevi for growth, with excellent sensitivity, specificity, PPV, and NPV.<\/jats:p>","DOI":"10.1159\/000494977","type":"journal-article","created":{"date-parts":[[2018,12,13]],"date-time":"2018-12-13T22:01:33Z","timestamp":1544738493000},"page":"298-302","source":"Crossref","is-referenced-by-count":10,"title":["Tele-Oncology: A Validation Study of Choroidal and Iris Nevi"],"prefix":"10.1159","volume":"5","author":[{"given":"Kelsey","family":"Roelofs","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6862-0850","authenticated-orcid":false,"given":"Ezekiel","family":"Weis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2018,12,13]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0b013e3283459508"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2009.02870.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2013.06.029"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2014.1604"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0113779"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcjo.2017.11.021"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2010.06.006"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.118.3.360"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2015-307168"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2017.05.026"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2011-301378"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcjo.2013.01.017"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.116.5.645"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2011.05.007.Prevalence"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1001\/archophthalmol.2008.625"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1001\/archophthalmol.2009.151"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2013.12.014"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S28863"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.3747\/co.23.2859"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2015.11.019"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2016.0913"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1001\/archophthalmol.2009.208"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19901001)66:7<1596::AID-CNCR2820660726>3.0.CO;2-6"}],"container-title":["Ocular Oncology and Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/494977","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/494977","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:09:47Z","timestamp":1745428187000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000494977"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,13]]},"references-count":23,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2019,6,28]]},"published-print":{"date-parts":[[2019,7,2]]}},"URL":"https:\/\/doi.org\/10.1159\/000494977","archive":["Portico"],"relation":{},"ISSN":["2296-4681","2296-4657"],"issn-type":[{"value":"2296-4681","type":"print"},{"value":"2296-4657","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12,13]]}}}