{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T02:40:13Z","timestamp":1792291213620,"version":"4.4.0"},"reference-count":21,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oncol Res Treat"],"published-print":{"date-parts":[[2019]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; The aim of this study was to investigate the association between body mass index (BMI) and prognosis of Chinese women with breast cancer. &lt;b&gt;&lt;i&gt;Patients and&lt;\/i&gt;&lt;\/b&gt; &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; 3,380 primary breast cancer patients who underwent surgery from 2010 to 2012 were selected and classified as low BMI group (BMI &amp;#x3c;\u00a025.0) and high BMI group (BMI \u2265\u00a025.0). The follow-up data for disease-free survival (DFS) and overall survival (OS) were obtained from 3,178 patients (median follow-up of 58 months). Cox regression analysis was used to evaluate the effect of BMI on DFS and OS. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; The high BMI group showed more aggressive pathological features. BMI was negatively associated with OS (hazard ratio (HR) 1.33, 95% confidence interval (CI) 1.06\u20131.66; p = 0.012) but not DFS (HR 1.15, 95% CI 0.94\u20131.40; p = 0.17). Furthermore, when stratified by age, BMI was significantly and negatively associated with OS (HR 1.43, 95% CI 1.05\u20131.95; p = 0.025) in patients above 50 years of age, but this effect was not detected in younger patients. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; BMI was an independent prognostic factor of OS in Chinese women with breast cancer, and age might be a mitigating factor. Among patients above 50 years of age, those with a high BMI were at greater risk of poor prognosis compared to individuals with a low BMI.<\/jats:p>","DOI":"10.1159\/000496548","type":"journal-article","created":{"date-parts":[[2019,3,8]],"date-time":"2019-03-08T22:00:52Z","timestamp":1552082452000},"page":"190-196","source":"Crossref","is-referenced-by-count":24,"title":["Body Mass Index at Diagnosis as a Prognostic Factor for Early-Stage Invasive Breast Cancer after Surgical Resection"],"prefix":"10.1159","volume":"42","author":[{"given":"Xue","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian-Li","family":"Hui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei-Qi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruo-Yang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen-Chuan","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2019,3,8]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1186\/s13058-015-0639-3"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(14)71123-4"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-07-1479"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.01.079"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-008-9203-0"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.29.7614"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-017-0528-4"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21405"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.22.4436"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.25.6529"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.50.9984"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-015-1879-4"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdu042"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-014-3002-y"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.26019"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0129741"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-015-3422-3"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.27.2021"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.40.8666"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-009-0512-0"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1186\/bcr3572"}],"container-title":["Oncology Research and Treatment"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/496548","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/496548","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:10:48Z","timestamp":1745424648000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000496548"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":21,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2019,4,5]]},"published-print":{"date-parts":[[2019,4,8]]}},"URL":"https:\/\/doi.org\/10.1159\/000496548","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.7819427","asserted-by":"subject"}]},"ISSN":["2296-5270","2296-5262"],"issn-type":[{"value":"2296-5270","type":"print"},{"value":"2296-5262","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019]]}}}