{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T15:02:44Z","timestamp":1791558164414,"version":"4.3.4"},"reference-count":10,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2019,2,28]],"date-time":"2019-02-28T00:00:00Z","timestamp":1551312000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2019,2,28]],"date-time":"2019-02-28T00:00:00Z","timestamp":1551312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Nephrol Dial"],"abstract":"<jats:p>Anti-glomerular basement membrane (anti-GBM) glomerulonephritis is a rare disease caused by autoantibodies against the glomerular basement membrane. Atypical anti-GBM nephritis is clinically less aggressive and characterized by the absence of circulating autoantibodies to the basement membrane. A previously healthy 53-year-old white woman presented with a rising creatinine over a short observation period. Renal biopsy, urinary sediment, and laboratory testing confirmed the diagnosis of atypical anti-GBM disease. She received plasmapheresis, steroids, and cyclophosphamide. She developed hemorrhagic cystitis early in the treatment from oral cyclophosphamide and mycophenolate mofetil was substituted as a first-line drug. She responded favorably and continued on mycophenolate mofetil without evidence of relapse. Despite the absence of circulating autoantibodies, a diagnosis of atypical anti-GBM nephritis should not be excluded if a high index of clinical suspicion exists. Early renal biopsy should be considered. Mycophenolate mofetil may be a reasonable replacement for oral cyclophosphamide in the treatment of atypical anti-GBM disease when cyclophosphamide is contraindicated.<\/jats:p>","DOI":"10.1159\/000498844","type":"journal-article","created":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T08:53:38Z","timestamp":1551430418000},"page":"8-14","source":"Crossref","is-referenced-by-count":8,"title":["Monotypic IgG1-kappa Atypical Anti-Glomerular Basement Membrane Nephritis: A Case Report"],"prefix":"10.1159","volume":"9","author":[{"given":"Maxim","family":"Olivier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harold","family":"Watson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viresh","family":"Mohanlal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Madruga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9867-8538","authenticated-orcid":false,"given":"Steven","family":"Carlan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2019,2,28]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1159\/000083133"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1093\/ckj\/sfv140"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2016.02.001"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-134-11-200106050-00009"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.5414\/CN107333"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0910500"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s40620-017-0394-x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2012.10.007"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2016.08.014"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2014.08.022"}],"container-title":["Case Reports in Nephrology and Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/498844","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/498844","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:22:48Z","timestamp":1745425368000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000498844"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,28]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2019,5,9]]}},"URL":"https:\/\/doi.org\/10.1159\/000498844","archive":["Portico"],"relation":{},"ISSN":["2296-9705"],"issn-type":[{"value":"2296-9705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,28]]}}}