{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T12:53:35Z","timestamp":1754398415015,"version":"3.40.4"},"reference-count":6,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2019,3,28]],"date-time":"2019-03-28T00:00:00Z","timestamp":1553731200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2019,3,28]],"date-time":"2019-03-28T00:00:00Z","timestamp":1553731200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Dermatol"],"abstract":"<jats:p>We report the case of a 73-year-old woman with leukoderma induced by cosmetics containing ascorbic acid. She had noticed the sudden appearance of a hypopigmented macule on the cheek within 1 month after use of the cosmetics with the brand name Obaji C Serum. No history of use of rhododenol-containing cosmetics was declared. Histopathological analysis revealed that the number of matured melanocytes was apparently decreased, and T lymphocytes abundantly infiltrated mainly the perifollicular region. In addition to the discontinuation of using Obaji C Serum, phototherapy by excimer light was noticeably effective for repigmentation. To our knowledge, there has been no other report so far showing hypopigmented lesions induced by this cosmetic.<\/jats:p>","DOI":"10.1159\/000499031","type":"journal-article","created":{"date-parts":[[2019,3,28]],"date-time":"2019-03-28T22:00:33Z","timestamp":1553810433000},"page":"86-90","source":"Crossref","is-referenced-by-count":1,"title":["An Extremely Rare Case of Leukoderma Induced by Cosmetics Containing Ascorbic Acid"],"prefix":"10.1159","volume":"11","author":[{"given":"Madoka","family":"Takafuji","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Tanemura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ichiro","family":"Katayama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2019,3,28]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2015.01.002"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/pcmr.12269"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2015.07.015"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.12744"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.14924\/dermatol.124.2095"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1042\/bj2950309"}],"container-title":["Case Reports in Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/499031","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/499031","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:24:11Z","timestamp":1745425451000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000499031"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,28]]},"references-count":6,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2019,5,2]]}},"URL":"https:\/\/doi.org\/10.1159\/000499031","archive":["Portico"],"relation":{},"ISSN":["1662-6567"],"issn-type":[{"type":"electronic","value":"1662-6567"}],"subject":[],"published":{"date-parts":[[2019,3,28]]}}}