{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T08:25:36Z","timestamp":1767169536906,"version":"build-2238731810"},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Curr Urol"],"published-print":{"date-parts":[[2020]]},"abstract":"<jats:p>Objective: We aimed to investigate the possible relationship between seminal parameters and cystatin C seminal levels in an infertility evaluation of chronic hemodialysis patients. Materials and Methods: This was a cross-sectional study, aged 18-60 years, in a group of 60 men undergoing hemodialysis (case) for more than 6 months, and a group of 15 healthy men (control) without clinical or laboratory signs of genitourinary tract infection. We performed a spermogram, hormonal profile, and assessment of leukocytes and cystatin levels in the semen. Results: The ages in the case and control were similar (p = 0.060).The seminal cystatin was significantly different between the case group and control group (41.16 \u00b1 26.59 vs. 79.00 \u00b1 05.68 mg\/l, respectively, p &lt; 0.001) and between normospermia and oligospermia (83.50 \u00b1 02.40 vs. 30.34 \u00b1 02.52 mg\/l, respectively, p &lt; 0.001). The mean seminal cystatin levels identified by the degrees of oligospermia (severe, moderate, and slim) were similar to each other (p &gt; 0.05) and significantly different (p &lt; 0.05) in relation to normospermia in the case group. The seminal cystatin levels positively correlated (p &lt; 0.05) with sperm motility and sperm density. Conclusion: Seminal cystatin levels are associated with the numerical and motility changes evidenced in the spermogram and may be of help in the initial evaluation of clinical suspicion of sub-fertility and infertility.<\/jats:p>","DOI":"10.1159\/000499241","type":"journal-article","created":{"date-parts":[[2021,1,9]],"date-time":"2021-01-09T08:18:43Z","timestamp":1610180323000},"page":"178-182","source":"Crossref","is-referenced-by-count":2,"title":["Cystatin C and Seminal Parameter Evaluation in Patients with End-Stage Renal Disease"],"prefix":"10.1097","volume":"14","author":[{"given":"Vitor Pereira Xavier","family":"Grangeiro","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2020,12,18]]},"updated-by":[{"DOI":"10.1097\/cu9.0000000000000048","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000}}],"container-title":["Current Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/499241","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/499241","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,11]],"date-time":"2021-01-11T04:29:23Z","timestamp":1610339363000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.karger.com\/Article\/FullText\/499241"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,12,18]]}},"URL":"https:\/\/doi.org\/10.1159\/000499241","archive":["Portico"],"relation":{},"ISSN":["1661-7649","1661-7657"],"issn-type":[{"value":"1661-7649","type":"print"},{"value":"1661-7657","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020]]}}}