{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T13:19:45Z","timestamp":1790255985667,"version":"4.1.0"},"reference-count":76,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2019]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; &lt;i&gt;Cutibacterium acnes&lt;\/i&gt; has been identified as one of the main triggers of acne. However, increasing knowledge of the human skin microbiome raises questions about the role of other skin commensals, such as &lt;i&gt;Staphylococcus epidermidis&lt;\/i&gt;, in the physiopathology of this skin disease. &lt;b&gt;&lt;i&gt;Summary:&lt;\/i&gt;&lt;\/b&gt; This review provides an overview of current knowledge of the potential role of &lt;i&gt;S. epidermidis&lt;\/i&gt; in the physiopathology of acne. Recent research indicates that acne might be the result of an unbalanced equilibrium between &lt;i&gt;C. acnes&lt;\/i&gt; and &lt;i&gt;S. epidermidis,&lt;\/i&gt;according to dedicated interactions. Current treatments act on &lt;i&gt;C. acnes&lt;\/i&gt;only. Other treatment options may be considered, such as probiotics derived from &lt;i&gt;S. epidermidis&lt;\/i&gt; to restore the naturally balanced microbiota or through targeting the regulation of the host\u2019s AMP mediators. &lt;b&gt;&lt;i&gt;Key Messages:&lt;\/i&gt;&lt;\/b&gt; Research seems to confirm the beneficial role of &lt;i&gt;S. epidermidis&lt;\/i&gt; in acne by limiting &lt;i&gt;C. acnes&lt;\/i&gt; over-colonisation and inflammation.<\/jats:p>","DOI":"10.1159\/000499858","type":"journal-article","created":{"date-parts":[[2019,5,21]],"date-time":"2019-05-21T21:01:17Z","timestamp":1558472477000},"page":"287-294","source":"Crossref","is-referenced-by-count":140,"title":["&lt;b&gt;&lt;i&gt;Staphylococcus epidermidis&lt;\/i&gt;&lt;\/b&gt;: A Potential New Player in the Physiopathology of 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