{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:52:08Z","timestamp":1787017928586,"version":"build-2736575974"},"reference-count":33,"publisher":"S. Karger AG","issue":"1-2","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiology"],"published-print":{"date-parts":[[2019]]},"abstract":"<b><i>Background:<\/i><\/b> Data regarding the prognostic impact of atrial fibrillation (AF) in patients with electrical storm (ES) is rare. <b><i>Objectives:<\/i><\/b> This study sought to assess the prognostic impact of AF in patients with ES on mortality, rehospitalization, major adverse cardiovascular events (MACE) and recurrence of ES (ES-R). <b><i>Methods:<\/i><\/b> All consecutive implantable cardioverter defibrillator (ICD) patients presenting with ES were included retrospectively from 2002 to 2016. Patients with AF were compared to non-AF patients. The primary prognostic endpoint was all-cause mortality. Secondary endpoints were in-hospital mortality, rehospitalization rates, MACE and ES-R. <b><i>Results:<\/i><\/b> A total of 87 ES patients with ICD were included and followed up to 2.5 years; 43% suffered from AF. The presence of AF was associated with increased all-cause mortality (47 vs. 29%, log-rank <i>p<\/i> = 0.052; hazard ratio [HR] 1.969, 95% confidence interval [CI] 0.981\u20133.952, <i>p<\/i> = 0.057), which was no longer present after multivariable adjustment for age, diabetes and dilated cardiomyopathy. Furthermore, AF was associated with increased rates of overall rehospitalization (61 vs. 31%, log-rank <i>p<\/i> = 0.013; HR 2.381, 95% CI 1.247\u20134.547, <i>p<\/i> = 0.009), especially due to AF (14 vs. 0%, <i>p<\/i> = 0.001) and acute heart failure (AHF) (28 vs. 10%, <i>p<\/i> = 0.018; HR 3.754, 95% CI 1.277\u201311.038, <i>p<\/i> = 0.016). Notably, AF was not associated with differences in MACE (55 vs. 37%, log rank <i>p<\/i> = 0.339) and ES-R (28 vs. 25%, log rank <i>p<\/i> = 0.704). <b><i>Conclusion:<\/i><\/b> In ES patients, presence of AF was univariably associated with increased rates of all-cause mortality at 2.5 years. Furthermore, AF was multivariably associated with overall rehospitalization, especially due to AF and AHF.<\/jats:p>","DOI":"10.1159\/000500262","type":"journal-article","created":{"date-parts":[[2019,9,17]],"date-time":"2019-09-17T17:00:31Z","timestamp":1568739631000},"page":"9-17","source":"Crossref","is-referenced-by-count":1,"title":["Prognostic Impact of Atrial Fibrillation in Electrical 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