{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T14:04:27Z","timestamp":1791813867704,"version":"4.3.4"},"reference-count":23,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neonatology"],"published-print":{"date-parts":[[2019]]},"abstract":"<b><i>Background:<\/i><\/b> Delaying cord clamping is recommended in order to assure placental transfusion. However, the evidence on cord management in elective cesarean section (CS) is limited. <b><i>Objective:<\/i><\/b> To compare delayed cord clamping (DCC) with early cord clamping (ECC) with regard to postnatal adaptation in neonates born through elective CS. <b><i>Methods:<\/i><\/b> All neonates born \u226539 weeks\u2019 gestation born through elective CS were assigned to either the DCC or the ECC arm at a 1:1 ratio according to a computer-generated, randomized sequence. The primary outcome was the hematocrit at day 2 of life. Secondary outcomes included: preductal oxygen saturation and heart rate during the first 10 min of life; transcutaneous bilirubin at day 3; and neonatal blood pressures in the first 3 days of life. Additional outcomes included: time to\u00a0first spontaneous breath; temperature at admission to normal nursery; weight at discharge; and maternal blood losses. <b><i>Results:<\/i><\/b> Eighty neonates were randomized to the DCC (<i>n<\/i> = 40) or the ECC (<i>n<\/i> = 40) arm. The hematocrit at day 2 was significantly higher in the DCC arm than in the ECC arm (mean difference: 6%; 95% CI 3\u20138; <i>p<\/i> &#x3c; 0.0001). The secondary outcome measures were not statistically different between the two arms. No infants needed phototherapy for hyperbilirubinemia during their hospital stay. <b><i>Conclusions:<\/i><\/b> Delaying cord clamping beyond 60 s increases the hematocrit at day 2 in neonates born through elective CS, without affecting maternal blood losses. Our findings suggest that DCC should be recommended in elective CS, but further studies are warranted to assess long-term outcomes.<\/jats:p>","DOI":"10.1159\/000500325","type":"journal-article","created":{"date-parts":[[2019,7,2]],"date-time":"2019-07-02T21:00:38Z","timestamp":1562101238000},"page":"252-259","source":"Crossref","is-referenced-by-count":40,"title":["Delayed Cord Clamping versus Early Cord Clamping in Elective Cesarean Section: A Randomized Controlled Trial"],"prefix":"10.1159","volume":"116","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0831-3971","authenticated-orcid":false,"given":"Francesco","family":"Cavallin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatrice","family":"Galeazzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vittoria","family":"Loretelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefania","family":"Madella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Pizzolato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Visentin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6462-0079","authenticated-orcid":false,"given":"Daniele","family":"Trevisanuto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2019,7,2]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2013-305703"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2017.00001"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2016.151"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(69)92328-9"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2015.07.029"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000276"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000001860"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2008.07.002"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2014.01.026"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2013.10.011"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-201212000-00045"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(77)90687-1"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-197404000-00645"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(75)90977-1"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-012995"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2015-308304"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD004074.pub3"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2016.3971"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2015.0358"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2018.06.006"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2012.250084"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-0467"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2017.10.231"}],"container-title":["Neonatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/500325","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/500325","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:36:34Z","timestamp":1745426194000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000500325"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":23,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2019,10,8]]},"published-print":{"date-parts":[[2019,10,15]]}},"URL":"https:\/\/doi.org\/10.1159\/000500325","archive":["Portico"],"relation":{},"ISSN":["1661-7800","1661-7819"],"issn-type":[{"value":"1661-7800","type":"print"},{"value":"1661-7819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019]]}}}