{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T21:23:25Z","timestamp":1788211405607,"version":"build-2803163510"},"reference-count":27,"publisher":"Bioscientifica","issue":"5","license":[{"start":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T00:00:00Z","timestamp":1771286400000},"content-version":"vor","delay-in-days":2409,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["journals.bioscientifica.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2019,10,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Background: Subacute thyroiditis is generally believed to be induced by viral infection, and little attention has been paid to anti-thyroid antibodies. Objectives: Our study aimed to assess the prevalence of anti-thyroid antibodies in patients with subacute thyroiditis. Methods: Anti-thyroglobulin (TgAb) and anti-thyroid peroxidase antibodies (TPOAb) were measured with 4 different immunoassay kits currently used in 40 patients in the early phase of subacute thyroiditis. Results: The proportion of samples positive for TgAb was 52.5 \u00b1 13.7% (mean of 4 kits), which was significantly (p &amp;lt; 0.05) higher than that positive for TPOAb (15.6 \u00b1 6.5%). The prevalence of positive TgAb alone (negative TPOAb) was also significantly higher than that of TPOAb alone (negative TgAb). TgAb titers decreased or disappeared within 4 months to 6 years in 6 patients. Conclusions: Patient samples were moderately positive for TgAb initially, but the titer decreased or disappeared afterwards in subacute thyroiditis.<\/jats:p>","DOI":"10.1159\/000501033","type":"journal-article","created":{"date-parts":[[2019,7,15]],"date-time":"2019-07-15T17:00:34Z","timestamp":1563210034000},"page":"268-272","update-policy":"https:\/\/doi.org\/10.1530\/crossmarkpolicy-17","source":"Crossref","is-referenced-by-count":33,"title":["Moderate Frequency of Anti-Thyroglobulin Antibodies in the Early Phase of Subacute Thyroiditis"],"prefix":"10.1530","volume":"8","author":[{"given":"Eijun","family":"Nishihara","sequence":"first","affiliation":[{"name":"1Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuyuki","family":"Amino","sequence":"additional","affiliation":[{"name":"1Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takumi","family":"Kudo","sequence":"additional","affiliation":[{"name":"1Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuyoshi","family":"Kohsaka","sequence":"additional","affiliation":[{"name":"1Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuru","family":"Ito","sequence":"additional","affiliation":[{"name":"1Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuji","family":"Fukata","sequence":"additional","affiliation":[{"name":"1Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsushige","family":"Nishikawa","sequence":"additional","affiliation":[{"name":"1Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirotoshi","family":"Nakamura","sequence":"additional","affiliation":[{"name":"1Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Miyauchi","sequence":"additional","affiliation":[{"name":"1Kuma Hospital, Center for Excellence in Thyroid Care, Kobe, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"416","published-online":{"date-parts":[[2019,7,15]]},"reference":[{"issue":"8","key":"2026070712590021900_ref1","doi-asserted-by":"publisher","first-page":"725","DOI":"10.2169\/internalmedicine.47.0740","article-title":"Clinical characteristics of 852 patients with subacute thyroiditis before treatment","volume":"47","author":"Nishihara","year":"2008","journal-title":"Intern Med","ISSN":"https:\/\/id.crossref.org\/issn\/0918-2918","issn-type":"print"},{"key":"2026070712590021900_ref2","unstructured":"Shrestha\n              RT\n            , HennesseyJ. Acute and Subacute, and Riedel\u2019s Thyroiditis. In: FeingoldKR, AnawaltB, BoyceA, ChrousosG, DunganK, GrossmanA, et al., editors. Endotext. South Dartmouth (MA); 2000."},{"key":"2026070712590021900_ref3","unstructured":"Farwell\n              A\n            \n          . Sporadic painless, painful subacute and acute infectious thyroiditis. A Fundemental and Clinical Text Braverman LE, Utiger RD The Thyroid. Tenth edition ed: Philadelphia: Lippincott Williams & Wilkins (LWW); 2013. p. 414\u201329."},{"issue":"3","key":"2026070712590021900_ref4","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1089\/thy.2012.0459","article-title":"Initial treatment with 15 mg of prednisolone daily is sufficient for most patients with subacute thyroiditis in Japan","volume":"23","author":"Kubota","year":"2013","journal-title":"Thyroid","ISSN":"https:\/\/id.crossref.org\/issn\/1050-7256","issn-type":"print"},{"issue":"1","key":"2026070712590021900_ref5","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/1743-422X-6-5","article-title":"Viruses and thyroiditis: an update","volume":"6","author":"Desailloud","year":"2009","journal-title":"Virol J","ISSN":"https:\/\/id.crossref.org\/issn\/1743-422X","issn-type":"print"},{"issue":"2","key":"2026070712590021900_ref6","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1007\/BF03343982","article-title":"Subacute thyroiditis in an immunosuppressed patient","volume":"25","author":"Obuobie","year":"2002","journal-title":"J Endocrinol Invest","ISSN":"https:\/\/id.crossref.org\/issn\/0391-4097","issn-type":"print"},{"issue":"6","key":"2026070712590021900_ref7","first-page":"956","article-title":"Wegener\u2019s granulomatosis with a possible thyroidal involvement","volume":"98","author":"Ozdogu","year":"2006","journal-title":"J Natl Med Assoc","ISSN":"https:\/\/id.crossref.org\/issn\/0027-9684","issn-type":"print"},{"issue":"2","key":"2026070712590021900_ref8","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1111\/j.1365-2265.1976.tb02822.x","article-title":"Measurement of circulating thyroid microsomal antibodies by the tanned red cell haemagglutination technique: its usefulness in the diagnosis of autoimmune thyroid diseases","volume":"5","author":"Amino","year":"1976","journal-title":"Clin Endocrinol (Oxf)","ISSN":"https:\/\/id.crossref.org\/issn\/0300-0664","issn-type":"print"},{"issue":"10","key":"2026070712590021900_ref9","doi-asserted-by":"publisher","first-page":"955","DOI":"10.1507\/endocrj.EJ17-0164","article-title":"Comparison of thyroglobulin and thyroid peroxidase antibodies measured by five different kits in autoimmune thyroid diseases","volume":"64","author":"Nishihara","year":"2017","journal-title":"Endocr J","ISSN":"https:\/\/id.crossref.org\/issn\/0918-8959","issn-type":"print"},{"issue":"896","key":"2026070712590021900_ref10","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1136\/pmj.76.896.345","article-title":"Status of antithyroid antibodies in Bangladesh","volume":"76","author":"Hasanat","year":"2000","journal-title":"Postgrad Med J","ISSN":"https:\/\/id.crossref.org\/issn\/0032-5473","issn-type":"print"},{"issue":"4","key":"2026070712590021900_ref11","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1590\/S0100-879X1999000400012","article-title":"Reactivity of anti-thyroid antibodies to thyroglobulin tryptic fragments: comparison of autoimmune and non-autoimmune thyroid diseases","volume":"32","author":"Boechat","year":"1999","journal-title":"Braz J Med Biol Res","ISSN":"https:\/\/id.crossref.org\/issn\/0100-879X","issn-type":"print"},{"issue":"1","key":"2026070712590021900_ref12","first-page":"1","article-title":"Persistent thyroid autoimmunity after subacute thyroiditis","volume":"23","author":"Weetman","year":"1987","journal-title":"J Clin Lab Immunol","ISSN":"https:\/\/id.crossref.org\/issn\/0141-2760","issn-type":"print"},{"issue":"8","key":"2026070712590021900_ref13","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1007\/s40618-017-0655-5","article-title":"Painful Hashimoto\u2019s thyroiditis: myth or reality?","volume":"40","author":"Rotondi","year":"2017","journal-title":"J Endocrinol Invest","ISSN":"https:\/\/id.crossref.org\/issn\/0391-4097","issn-type":"print"},{"key":"2026070712590021900_ref14","unstructured":"JapanThyroidAssociation\n          . 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