{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T10:55:14Z","timestamp":1772276114180,"version":"3.50.1"},"reference-count":27,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Princ Pract"],"published-print":{"date-parts":[[2019]]},"abstract":"<b><i>Objective:<\/i><\/b> To evaluate multidetector computed tomography (MDCT) findings in patients with achalasia, to assess its role in differentiating subtypes in detecting lung involvement and extra-esophageal thoracic complications. <b><i>Subjects and Methods:<\/i><\/b> This clinical retrospective study included 51 patients with manometrically confirmed achalasia who underwent chest X-ray and MDCT in diagnostic work-up. Esophageal wall thickness and morphology, luminal dilatation, lung changes, and extra-esophageal manifestations were analyzed on MDCT by 2 readers. Wilcoxon, Kruskal-Wallis and Mann-Whitney test were used for assessing the differences among the achalasia subtypes, and intra-class correlation coefficients (ICC) assessing the inter-observer agreement between the measurements of 2 readers. <b><i>Results:<\/i><\/b> Fourteen (27.5%) patients had achalasia subtype I, 21 (60.8%) had subtype II while 6 (11.8%) had subtype III. Esophageal wall thickness of the esophageal body (EB) and distal esophageal segment (DES) as well as nodular\/lobulated appearance of DES were found significantly more often in subtype III (<i>p<\/i> = 0.024, <i>p<\/i> &#x3c; 0.001, <i>p<\/i> = 0.009, respectively). Esophageal dilatation gradually decreased from subtype I to III (<i>p<\/i> = 0.006). Chest X-ray revealed lung changes in 9 (17%) and MDCT in 21 (41%) patients (<i>p<\/i> = 0.001), most frequently in subtype I, with predominance of ground-glass opacities. Tracheal\/carinal compression was detected in 27 (52.9%) and left atrial compression in 17 (33.3%) patients. Excellent inter-observer agreement was observed in measuring the EB and DES wall thickness, and diameter of EB (ICC 0.829, 0.901, and 0.922). <b><i>Conclusion:<\/i><\/b> MDCT is a useful tool for detecting lung and extra-esophageal thoracic complications in patients with achalasia, and could be a valuable additional imaging modality in the differentiation of achalasia subtypes.<\/jats:p>","DOI":"10.1159\/000501057","type":"journal-article","created":{"date-parts":[[2019,5,22]],"date-time":"2019-05-22T21:01:42Z","timestamp":1558558902000},"page":"539-546","source":"Crossref","is-referenced-by-count":9,"title":["Value of Multidetector Computed Tomography in the Assessment of Achalasia Subtypes and Detection of Pulmonary and Thoracic Complications"],"prefix":"10.1159","volume":"28","author":[{"given":"Sanja","family":"Jovanovic","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksandra","family":"Djuric-Stefanovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksandar","family":"Simi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ognjan","family":"Skrobic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Predrag","family":"Pesko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2019,5,22]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2005.41775.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1999.01639.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-009-1042-0"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.07.022"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-010-1318-4"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)60651-0"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-017-5570-5"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2012.07.019"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1159\/000343902"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-2980.2012.00622.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2050.2010.01126.x"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1213\/XAA.0000000000000064"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-007-9290-5"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2014.05.005"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2009.01268.x"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.50.5603"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A1334"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.case.2018.07.002"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-199105000-00016"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1148\/radiographics.22.suppl_1.g02oc18s247"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2272012051"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2010.01511.x"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.4103\/1319-3767.157560"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2008.09.002"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.07.3747"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.5056\/jnm.2013.19.2.126"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00459.2015"}],"container-title":["Medical Principles and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/501057","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/501057","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:43:46Z","timestamp":1745426626000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000501057"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":27,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2019,11,28]]},"published-print":{"date-parts":[[2019,12,9]]}},"URL":"https:\/\/doi.org\/10.1159\/000501057","archive":["Portico"],"relation":{},"ISSN":["1011-7571","1423-0151"],"issn-type":[{"value":"1011-7571","type":"print"},{"value":"1423-0151","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019]]}}}