{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T22:45:40Z","timestamp":1770417940802,"version":"3.49.0"},"reference-count":9,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2019,8,13]],"date-time":"2019-08-13T00:00:00Z","timestamp":1565654400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2019,8,13]],"date-time":"2019-08-13T00:00:00Z","timestamp":1565654400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Ophthalmol"],"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Purpose:&lt;\/i&gt;&lt;\/b&gt; To present a case of peripheral ulcerative keratitis with perforation in the setting of syphilis. &lt;b&gt;&lt;i&gt;Method:&lt;\/i&gt;&lt;\/b&gt; A single observational case report in urban USA. &lt;b&gt;&lt;i&gt;Case Presentation:&lt;\/i&gt;&lt;\/b&gt; A patient with multiple sexual partners presented with bilateral peripheral ulcerative keratitis, unilateral corneal perforation, and a pustular rash. Workup was positive for syphilis as well as HSV, HIV, and multiple autoantibody tests. Findings improved after treatment for syphilis. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Bilateral peripheral ulcerative keratitis in syphilis has been reported in one prior case. However, corneal perforation in the setting of syphilis infection has not, to our knowledge, been reported previously.<\/jats:p>","DOI":"10.1159\/000501996","type":"journal-article","created":{"date-parts":[[2019,8,13]],"date-time":"2019-08-13T21:00:36Z","timestamp":1565730036000},"page":"267-273","source":"Crossref","is-referenced-by-count":6,"title":["Perforating Peripheral Ulcerative Keratitis in Syphilis"],"prefix":"10.1159","volume":"10","author":[{"given":"Pimpiroon","family":"Ploysangam","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth\u00a0Marie","family":"Mattern","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2019,8,13]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfo.2012.12.004"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tjo.2016.06.002"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.12337"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e31822f3c18"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-199609000-00002"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3121\/cmr.3.3.190"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-07137-4"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S1568-9972(02)00086-1"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000006230"}],"container-title":["Case Reports in Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/501996","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/501996","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:47:19Z","timestamp":1745423239000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000501996"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,13]]},"references-count":9,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2019,9,3]]}},"URL":"https:\/\/doi.org\/10.1159\/000501996","archive":["Portico"],"relation":{},"ISSN":["1663-2699"],"issn-type":[{"value":"1663-2699","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,13]]}}}