{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:25:32Z","timestamp":1745468732692,"version":"3.40.4"},"reference-count":29,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Obes Facts"],"published-print":{"date-parts":[[2019]]},"abstract":"<b><i>Background:<\/i><\/b> Weight control through lifestyle interventions represents a suitable strategy to avoid the metabolic, endocrine, and reproductive comorbidities associated with overweight and obesity. Reduced testosterone (T) levels are a worsening factor in overweight males. However, prognostic parameters of long-term weight loss are not readily available. Here, we tested the prognostic value of early variations of anthropometric and hormonal parameters, with a focus on ultrasound stratigraphy (US) and the reduction in body mass index (BMI) associated with nutritional counseling\/lifestyle interventions at 6-month follow-up. <b><i>Methods:<\/i><\/b> Ninety-five male subjects (BMI 25\u201334.9 kg\/m<sup>2<\/sup>) who had undergone nutritional\/lifestyle interventions, were retrospectively analyzed for: body weight and composition; US evaluation at the triceps (TRC), abdominal (ABD), and thigh (THI) areas; and circulating levels of T, luteinizing hormone, and follicle-stimulating hormone. Sixty patients (63.2%) completed the 6-month follow-up program. <b><i>Results:<\/i><\/b> At 6 months, a significant reduction in BMI (26.38 \u00b1 1.55 vs. 31.5 \u00b1 5.0 basal, <i>p<\/i> &#x3c; 0.001) and increase in T levels (18 \u00b1 5.4 vs. 9.5 \u00b1 2.3 nmol\/L basal, <i>p<\/i> = 0.04) were observed. Subjects in the highest quartile of the BMI reduction at 6 months (\u0394BMI 6 mo), compared to the lowest, showed a significant difference at the 2-month follow-up variation of BMI (<i>p<\/i> = 0.025), and fat and muscle thickness at the TRC (both <i>p<\/i> &#x3c; 0.001) and ABD (<i>p<\/i> &#x3c; 0.001 and <i>p<\/i> = 0.002, respectively) areas. Variation of TRC muscle thickness at 2 months was the only independent predictor of \u0394BMI 6 mo in the multiple stepwise regression analysis. <b><i>Conclusions:<\/i><\/b> BMI evaluation and US represent useful monitoring tools in the follow-up of nutritional\/lifestyle interventions for overweight-to-mildly obese patients. The important effects on motivation and adherence to the intervention program are to be considered.<\/jats:p>","DOI":"10.1159\/000502119","type":"journal-article","created":{"date-parts":[[2019,11,8]],"date-time":"2019-11-08T22:00:30Z","timestamp":1573250430000},"page":"606-617","source":"Crossref","is-referenced-by-count":2,"title":["Prognostic Value of Ultrasound Stratigraphy in Long-Term Weight Loss: Results from a Nutritional Counseling Program"],"prefix":"10.1159","volume":"12","author":[{"given":"Luca","family":"De\u00a0Toni","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel\u00a0Cosmin","family":"Petre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Garolla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilaria","family":"De\u00a0Santis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umberto","family":"Valente","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Foresta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maurizio","family":"De\u00a0Rocco\u00a0Ponce","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2019,11,8]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/cen.12722"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-70178-3_26"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/obr.12282"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2014.09.008"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.4414\/smw.2016.14283"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/jsm.12146"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.10432"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-12-1100"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s00221-018-5305-4"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16986-9"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2016.02.005"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2016.09.014"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0058533"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1186\/2049-3258-72-3"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2013.04.014"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-2329F"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4603(96)00068-8"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2003.122"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/S1471-0153(03)00029-1"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3999(86)90029-2"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4603(84)90044-3"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1080\/07315724.2009.10719767"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1017\/S1368980009992977"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa050156"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2009.05.004"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2017.167"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2015-095641"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2013-092233"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2013-092232"}],"container-title":["Obesity Facts"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/502119","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/502119","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:48:36Z","timestamp":1745423316000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000502119"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":29,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2019,12,18]]},"published-print":{"date-parts":[[2019,12,20]]}},"URL":"https:\/\/doi.org\/10.1159\/000502119","archive":["Portico"],"relation":{},"ISSN":["1662-4025","1662-4033"],"issn-type":[{"type":"print","value":"1662-4025"},{"type":"electronic","value":"1662-4033"}],"subject":[],"published":{"date-parts":[[2019]]}}}