{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T09:01:26Z","timestamp":1769504486577,"version":"3.49.0"},"reference-count":18,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2019,10,4]],"date-time":"2019-10-04T00:00:00Z","timestamp":1570147200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2019,10,4]],"date-time":"2019-10-04T00:00:00Z","timestamp":1570147200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Appendage Disord"],"published-print":{"date-parts":[[2020]]},"abstract":"<b><i>Introduction:<\/i><\/b> Androgenetic alopecia (AGA) is a common, chronic hair loss disorder. Platelet-rich plasma (PRP) is a novel therapeutic tool for AGA. The objective of this study was to assess the clinical efficacy and safety of autologous activated PRP injections in AGA. <b><i>Methods:<\/i><\/b> Twenty-four AGA patients were enrolled in the study. All the patients received 4 PRP treatments at baseline (T1), 3 weeks (T2), 6 weeks (T3), and at 14 weeks (T5). We evaluated hair density (hairs\/cm<sup>2<\/sup>) at 6 time points (T1\u2013T3, T4 [9 weeks], T5, and T6 [7 months]) and patient satisfaction was assessed at T6 with a patient satisfaction questionnaire. Hair count (hairs\/0.48 cm<sup>2<\/sup>) was assessed using dermoscopic photographs and hair density (hairs\/cm<sup>2<\/sup>) was calculated accordingly. <b><i>Results:<\/i><\/b> Twenty-three men and one woman were included with baseline hair density of 102.25 \u00b1 18.463. Hair density significantly increased at all time points with <i>p<\/i> &#x3c; 0.001 compared to the baseline. Patients were satisfied with a mean result rating of 72.92 on a linear analogue scale of 0\u2013100. Other than mild pain felt during injections, no remarkable adverse effects were noted. <b><i>Conclusions:<\/i><\/b> PRP injections may have a positive therapeutic effect on AGA without major side effects.<\/jats:p>","DOI":"10.1159\/000502919","type":"journal-article","created":{"date-parts":[[2019,10,4]],"date-time":"2019-10-04T21:00:34Z","timestamp":1570222834000},"page":"19-24","source":"Crossref","is-referenced-by-count":13,"title":["The Clinical Efficacy and Safety of Autologous Activated Platelet-Rich Plasma Injection in Androgenetic Alopecia"],"prefix":"10.1159","volume":"6","author":[{"given":"Niluka\u00a0Dilrukshi","family":"Paththinige","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janaka\u00a0K.W.","family":"Akarawita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geetha","family":"Jeganathan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2019,10,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1087-0024.2005.10102.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1185\/030079905X61820"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(93)70223-G"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1517\/14656561003752730"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0379.2011.07802.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1242033"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097\/01.PRS.0000138251.07040.51"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1054\/jcms.2002.0285"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/532519"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12616668"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097\/01.prs.0000239560.29172.33"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3109\/09546630903578574"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2004.01.002"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2000.103272"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1177\/120347540200600101"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2012.02378.x"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2012.02394.x"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1006\/excr.1997.3601"}],"container-title":["Skin Appendage Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/502919","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/502919","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:56:18Z","timestamp":1745423778000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000502919"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,4]]},"references-count":18,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2020,1,21]]},"published-print":{"date-parts":[[2020,1,21]]}},"URL":"https:\/\/doi.org\/10.1159\/000502919","archive":["Portico"],"relation":{},"ISSN":["2296-9195","2296-9160"],"issn-type":[{"value":"2296-9195","type":"print"},{"value":"2296-9160","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,4]]}}}