{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T03:46:34Z","timestamp":1770522394150,"version":"3.49.0"},"reference-count":16,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2019,11,8]],"date-time":"2019-11-08T00:00:00Z","timestamp":1573171200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2019,11,8]],"date-time":"2019-11-08T00:00:00Z","timestamp":1573171200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiology"],"published-print":{"date-parts":[[2020]]},"abstract":"<b><i>Introduction:<\/i><\/b> Recurrent ventricular tachycardia (VT) after percutaneous ablation is associated with a high morbidity and mortality. We assessed the feasibility of open chest extracorporeal circulation (ECC)-supported 3D multielectrode mapping and targeted VT substrate ablation in patients with previously failed percutaneous endocardial and epicardial VT ablations. <b><i>Methods:<\/i><\/b> In patients with previously failed percutaneous endocardial and epicardial VT ablations and a high risk of hemodynamic collapse during the procedure, open chest ECC-supported mapping and ablation were performed in a hybrid EP lab setting. Electro-anatomic maps (3D) were acquired during sinus rhythm and VT using a multielectrode mapping catheter (HD grid; Abbott or Pentaray, Biosense Webster). Irrigated radiofrequency ablations of all inducible VT were performed with a contact force ablation catheter. <b><i>Results:<\/i><\/b> Hybrid VT ablation was performed in 5 patients with structural heart disease (i.e., 3 with previous old myocardial infarction and 2 with nonischemic cardiomy\u00adopathy) and recurrent VT. Acute procedural success was achieved in all patients. Four patients were successfully weaned off the ECC. In 1 patient with a severely reduced LVEF (16%), damage to the venous graft occurred after sternotomy and that patient died after 1 month. Four patients (80%) remained VT free after a median follow-up of 6 (IQR 4\u201310) months. <b><i>Conclusion:<\/i><\/b> In high-risk patients with previously failed percutaneous endocardial and epicardial VT ablations, open chest ECC-supported multielectrode epicardial mapping revealed a VT substrate in all of the patients, and targeted epicardial ablation abolished VT substrate in these patients.<\/jats:p>","DOI":"10.1159\/000503251","type":"journal-article","created":{"date-parts":[[2019,11,8]],"date-time":"2019-11-08T22:00:30Z","timestamp":1573250430000},"page":"88-94","source":"Crossref","is-referenced-by-count":1,"title":["Hybrid Ventricular Tachycardia Ablation after Failed Percutaneous Endocardial and Epicardial Ablation"],"prefix":"10.1159","volume":"145","author":[{"given":"Danielle\u00a0M.","family":"Haanschoten","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"Adiyaman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaap\u00a0Jan\u00a0J.","family":"Smit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter\u00a0Paul\u00a0H.M.","family":"Delnoy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anand\u00a0R.","family":"Ramdat\u00a0Misier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabiano","family":"Porta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert\u00a0P.H.","family":"Storm\u00a0van\u00a0Leeuwen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arif","family":"Elvan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2019,11,8]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2018.08.010"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.10.084"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2010.07.009"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2017.11.009"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eus210"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000125525.04081.4B"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.109.859942"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000140725.42845.90"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1023\/B:JICE.0000026925.41543.7c"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/471397"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1177\/0267659118814689"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.111.962555"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrcr.2017.10.007"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12839"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.116.004492"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2018.08.009"}],"container-title":["Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/503251","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/503251","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:59:05Z","timestamp":1745423945000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000503251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,8]]},"references-count":16,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2020,2,4]]},"published-print":{"date-parts":[[2020,2,11]]}},"URL":"https:\/\/doi.org\/10.1159\/000503251","archive":["Portico"],"relation":{},"ISSN":["0008-6312","1421-9751"],"issn-type":[{"value":"0008-6312","type":"print"},{"value":"1421-9751","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,8]]}}}