{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T21:11:27Z","timestamp":1787605887686,"version":"build-2736575974"},"reference-count":15,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2019,10,23]],"date-time":"2019-10-23T00:00:00Z","timestamp":1571788800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2019,10,23]],"date-time":"2019-10-23T00:00:00Z","timestamp":1571788800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Ophthalmol"],"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Purpose:&lt;\/i&gt;&lt;\/b&gt; This study investigated the clinical outcomes achieved with a newly developed donor inserter (NS Endo-Inserter [NSI], HOYA Co., Ltd., Tokyo, Japan) for Descemet\u2019s stripping automated endothelial keratoplasty (DSAEK) in Japanese eyes with bullous keratopathy secondary to argon laser iridotomy (BK-ALI). The NSI device utilizes pressure flow to push the DSAEK donor tissue into the anterior chamber. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; Six eyes of 6 patients (1 male, 5 females; mean age, 78.5 years) with BK-ALI were enrolled. Donor tissue was pushed into the anterior chamber using the NSI. Intraoperative complications, graft dislocation, and iatrogenic primary graft failure were recorded for all eyes. Six-month postoperative central donor endothelial cell densities (ECD) were measured prospectively and compared with preoperative values, along with 6-month best corrected visual acuity (BCVA). &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; In all cases, donor loading onto the NSI spatula and donor insertion into the anterior chamber using the NSI was smooth and successful; no intraoperative complications were noted. There were no cases of graft dislocation or IPGF. Postoperative ECD was 2,187.2 cells\/mm&lt;sup&gt;2&lt;\/sup&gt; (mean loss, 14.8%) and mean BCVA increased from 0.27 decimal to 0.8 at 6 months. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; In this small preliminary case series, clinical outcomes for patients with BK-ALI undergoing DSAEK using the NSI were comparable or better than those achieved with conventional DSAEK insertion techniques.<\/jats:p>","DOI":"10.1159\/000503441","type":"journal-article","created":{"date-parts":[[2019,10,23]],"date-time":"2019-10-23T21:00:50Z","timestamp":1571864450000},"page":"357-364","source":"Crossref","is-referenced-by-count":5,"title":["Clinical Evaluation of the NS Endo-Inserter, a Novel Donor Inserter for Descemet\u2019s Stripping Automated Endothelial Keratoplasty"],"prefix":"10.1159","volume":"10","author":[{"given":"Akira","family":"Kobayashi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideaki","family":"Yokogawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natsuko","family":"Mori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsubasa","family":"Nishino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuhisa","family":"Sugiyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2019,10,23]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ico.0000214224.90743.01"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2009.07.036"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e318182a4d3"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2007.06.050"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.126.8.1133"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e31817f38e9"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2010.08.027"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3928\/15428877-20120426-04"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000001302"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S182628"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S170263"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3928\/15428877-20111129-08"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2013.01.025"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e3182120f9d"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000000157"}],"container-title":["Case Reports in Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/503441","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/503441","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:01:07Z","timestamp":1745424067000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000503441"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,23]]},"references-count":15,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2019,12,20]]}},"URL":"https:\/\/doi.org\/10.1159\/000503441","archive":["Portico"],"relation":{},"ISSN":["1663-2699"],"issn-type":[{"value":"1663-2699","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,23]]}}}