{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T03:30:33Z","timestamp":1747193433450,"version":"3.40.5"},"reference-count":24,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2019,12,4]],"date-time":"2019-12-04T00:00:00Z","timestamp":1575417600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2019,12,4]],"date-time":"2019-12-04T00:00:00Z","timestamp":1575417600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2020]]},"abstract":"<b><i>Background:<\/i><\/b> Hidradenitis suppurativa (HS) is a chronic, recurrent, auto-inflammatory disease that affects the pilosebaceous unit in apocrine gland-bearing areas. Bacteria are thought to play a role in the development and progression of disease. In addition, antibiotics are frequently used as first-line management for HS. We sought to determine the carriage status of <i>Staphylococcus aureus<\/i> and its resistance to antibiotics among patients with HS in a tertiary referral hospital in Athens, Greece. <b><i>Methods:<\/i><\/b> In this observational cohort study, 68 consecutive patients attending the HS clinic of \u201cAttikon\u201d General University Hospital in Athens, Greece, during a 9-month period were enrolled. All patients had not received any antibiotic therapy for any reason during the previous 3 months before enrollment. Nasal and oropharyngeal sampling<i><\/i>were obtained, and specimens were tested for the presence of <i>S. aureus.<\/i>Antibiotic susceptibility testing was performed using the VITEK 2 system. Standard statistical tests, descriptive statistics tests, and \u03c7<sup>2<\/sup> and Pearson correlation tests were performed, using IBM SPSS Statistics 25<i>.<\/i>The level of significance was set at a <i>p<\/i>value &#x3c;0.05. <b><i>Results:<\/i><\/b> Sixty-eight patients with HS were studied. There were 44 females (64.7%) and 24 males (35.3%). The mean age was 36.63 \u00b1 13.0 (IQR = 21), and the mean age at onset of disease was 23.90 \u00b1 11.53 (IQR = 14). The mean duration of disease was 12.74 \u00b1 10.20 years (IQR = 15). Fifteen (22.1%) of the patients were Hurley stage I, 22 (32.4%) were Hurley stage II, and 31 (45.6%) were Hurley stage III. <i>S. aureus<\/i> carriage was detected in 17 patients (25%). Six of them (35.3%) had MRSA strains. There was an increased prevalence of <i>S. aureus<\/i> colonization (<i>p<\/i> = 0.058) and MRSA (<i>p<\/i> = 0.101) in Hurley stage III patients, but this result was not statistically significant. <b><i>Conclusions:<\/i><\/b> We found a 25% prevalence of <i>S. aureus<\/i> colonization (17\/68 patients) and a 35.3% prevalence of MRSA (6\/17) among our HS patients. There was an increased prevalence of <i>S. aureus<\/i>and MRSA positivity in HS patients with Hurley stage III. Further studies are needed to clarify the possible clinical significance of <i>S. aureus<\/i> carriage in the disease development and progression as well as in the treatment outcome.<\/jats:p>","DOI":"10.1159\/000504537","type":"journal-article","created":{"date-parts":[[2019,12,4]],"date-time":"2019-12-04T22:02:10Z","timestamp":1575496930000},"page":"31-36","source":"Crossref","is-referenced-by-count":10,"title":["<b><i>Staphylococcus aureus<\/i><\/b> Carriage Status in Patients with Hidradenitis Suppurativa: An Observational Cohort Study in a Tertiary Referral Hospital in Athens, Greece"],"prefix":"10.1159","volume":"236","author":[{"given":"Alexander","family":"Katoulis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasiliki","family":"Koumaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0466-7553","authenticated-orcid":false,"given":"Ourania","family":"Efthymiou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7074-2374","authenticated-orcid":false,"given":"Dimitra","family":"Koumaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evangelia","family":"Dimitroulia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Voudouri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Voudouri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evangelia","family":"Bozi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Athanasios","family":"Tsakris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2019,12,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2012.03.004"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(13)70036-7"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2013.03.020"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61999-1"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2008.00712.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12793"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2018.09.036"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12966"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1086\/520016"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0463.2011.02758.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.1.132-139.2005"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkw431"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa043252"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-011-1331-x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-2591"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.02419"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.08.001"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1159\/000381959"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1999.02613.x"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10747.x"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1159\/000246246"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1841"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.3201\/eid2012.140064"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-48-1-103"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/504537","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/504537","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:11:45Z","timestamp":1745424705000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000504537"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,4]]},"references-count":24,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2020,2,11]]},"published-print":{"date-parts":[[2020,2,13]]}},"URL":"https:\/\/doi.org\/10.1159\/000504537","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.11316335","asserted-by":"subject"}]},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"type":"print","value":"1018-8665"},{"type":"electronic","value":"1421-9832"}],"subject":[],"published":{"date-parts":[[2019,12,4]]}}}