{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T12:37:45Z","timestamp":1791376665105,"version":"4.3.2"},"reference-count":27,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T00:00:00Z","timestamp":1575244800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T00:00:00Z","timestamp":1575244800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Princ Pract"],"published-print":{"date-parts":[[2020]]},"abstract":"<b><i>Introduction:<\/i><\/b> Body temperature (BT) abnormalities are frequently observed in critically ill patients. We aimed to assess admission BT in a heterogeneous critically ill patient population admitted to an intensive care unit (ICU) as a prognostic parameter for intra-ICU and long-term mortality. <b><i>Methods:<\/i><\/b> A total of 6,514 medical patients (64 \u00b1 15 years) admitted to a German ICU between 2004 and 2009 were included. A follow-up of patients was performed retrospectively. The association of admission BT with both intra-ICU and long-term mortality was investigated by logistic regression. <b><i>Results:<\/i><\/b> Patients with hypothermia (&#x3c;36\u00b0C BT) were clinically worse and had more pronounced signs of multi-organ failure. Admission BT was associated with adverse overall outcome, with a 2-fold increase for hyperthermia (mortality 12%; odds ratio [OR] 1.80, 95% confidence interval [CI] 1.43\u20132.26; <i>p<\/i> &#x3c; 0.001), and a 4-fold increase for the risk of hypothermia (mortality 24%; OR 4.05, 95% CI 3.38\u20134.85; <i>p<\/i> &#x3c; 0.001) with respect to intra-ICU and long-term mortality. Moreover, hypothermia was even more harmful than hyperthermia, and both were strongly associated with intra-ICU mortality, especially in patients admitted with acute coronary syndrome (hypothermia: hazard ratio 6.12, 95% CI 4.12\u20139.11; <i>p<\/i> &#x3c; 0.001; hyperthermia: OR 2.70, 95% CI 1.52\u20134.79; <i>p<\/i>&#x3c; 0.001). <b><i>Conclusion:<\/i><\/b> Admission BT is an independent risk predictor for both overall intra-ICU and long-term mortality in critically ill patients admitted to an ICU. Therefore, BT at admission might not only serve as a parameter for individual risk stratification but can also influence individual therapeutic decision-making.<\/jats:p>","DOI":"10.1159\/000505126","type":"journal-article","created":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T22:00:30Z","timestamp":1575324030000},"page":"389-395","source":"Crossref","is-referenced-by-count":31,"title":["Admission Body Temperature in Critically Ill Patients as an Independent Risk Predictor for Overall Outcome"],"prefix":"10.1159","volume":"29","author":[{"given":"Ralf\u00a0","family":"Erkens","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard\u00a0","family":"Wernly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryna\u00a0","family":"Masyuk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna\u00a0M.","family":"Muessig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"Franz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul\u00a0Christian","family":"Schulze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael\u00a0","family":"Lichtenauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malte","family":"Kelm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2019,12,2]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181aa6117"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1989.00390070061006"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-004-2166-z"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1186\/cc9077"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s00540-016-2200-7"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e318170efd3"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200203000-00037"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-015-3672-x"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18091893"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0170987"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-019-05655-5"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1993.03510240069035"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-005-2763-5"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-017-1002-3"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.injury.2014.09.024"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31822f061d"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00668.2006"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199403000-00029"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.2741\/1858"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1186\/cc13773"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2016.01.001"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199210000-00006"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000002249"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1093\/eurjhf\/hft113"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-019-05668-0"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-019-05553-w"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.116.005463"}],"container-title":["Medical 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