{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T23:04:18Z","timestamp":1777417458660,"version":"3.51.4"},"reference-count":28,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiology"],"published-print":{"date-parts":[[2020]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Introduction:&lt;\/i&gt;&lt;\/b&gt; Changes in electrocardiogram (ECG) parameters and the incidence of arrhythmic events in patients with fever-induced Brugada syndrome (BrS) remain unknown. &lt;b&gt;&lt;i&gt;Objective:&lt;\/i&gt;&lt;\/b&gt; We aimed to investigate the effect of hyperthermia on the ECG pattern and the occurrence of fever-triggered arrhythmic events (FTAEs) in patients with fever-induced BrS. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; We retrospectively analyzed a series of fever-induced BrS cases from January 1966 to November 2018. Clinical characteristics and ECG parameters were evaluated in the presence or absence of fever. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Syncope and implantable cardioverter defibrillator implantation occurred more frequently in BrS patients with FTAEs than in patients without FTAEs. In BrS patients &amp;#x3c;16 years old, more arrhythmia events occurred in patients with FTAEs than in patients without FTAEs (&lt;i&gt;p&lt;\/i&gt; = 0.04). During follow-up, 2 patients in the FTAEs group suffered new malignant arrhythmic events. Compared to the afebrile state, the J point increased significantly in precordial leads V1, V2, and V3 during the febrile state (all &lt;i&gt;p&lt;\/i&gt; &amp;#x3c; 0.01). The corrected QTpeak intervals in V1 and V2 were significantly longer in the FTAEs group than in the non-FTAEs group (354.5 \u00b1 37.0 vs. 334.3 \u00b1 45.5 ms, &lt;i&gt;p&lt;\/i&gt; &amp;#x3c; 0.01 and 368.0 \u00b1 43.4 vs. 330.9 \u00b1 41.5 ms, &lt;i&gt;p&lt;\/i&gt; &amp;#x3c; 0.01, respectively). An increased corrected QT dispersion and a lengthened corrected Tpeak-Tend dispersion were also observed during fever. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; Fever may not only reveal BrS but also induce life-threatening arrhythmic events, especially in children and adolescents.<\/jats:p>","DOI":"10.1159\/000505642","type":"journal-article","created":{"date-parts":[[2020,2,3]],"date-time":"2020-02-03T22:00:30Z","timestamp":1580767230000},"page":"130-135","source":"Crossref","is-referenced-by-count":9,"title":["Electrocardiogram Characteristics and Arrhythmic Events during Fever in Patients with Fever-Induced Brugada Syndrome"],"prefix":"10.1159","volume":"145","author":[{"given":"Xinguang","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongyan","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenwu","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fengxiang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2020,2,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(92)90253-J"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000152479.54298.51"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.000901"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9592.2002.01646.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1046\/j.1540-8167.2003.02379.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S1099-5129(03)00029-1"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2011.12.009"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-1688"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.746495"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.12.049"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.74.1.84"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1161\/hc1102.105288"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1542-474X.2005.00055.x"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2018.04.007"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.664219"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000104568.13957.4F"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.08.064"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.887026"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2010.07.012"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.67.1.39"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(97)00301-X"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.63.6.342"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(88)90212-4"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.78.4.371"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.18.1928"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2004.02.002"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelectrocard.2013.02.001"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2015.07.029"}],"container-title":["Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/505642","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/505642","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:41:19Z","timestamp":1745422879000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000505642"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":28,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2020,3,13]]},"published-print":{"date-parts":[[2020,3,17]]}},"URL":"https:\/\/doi.org\/10.1159\/000505642","archive":["Portico"],"relation":{},"ISSN":["0008-6312","1421-9751"],"issn-type":[{"value":"0008-6312","type":"print"},{"value":"1421-9751","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020]]}}}