{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T03:10:46Z","timestamp":1777086646497,"version":"3.51.4"},"reference-count":12,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Appendage Disord"],"published-print":{"date-parts":[[2020]]},"abstract":"<jats:p>Intralesional (IL) injection of corticosteroids is an effective treatment of alopecia areata (AA). A novel drug delivery technique that uses a tattoo machine (MMP\u00ae) has been successfully used to treat other skin disorders. We tested this technique to treat AA. We used the Cheyenne dermopigmentation machine (Anvisa 80281110016; Germany) with a 27 Magnum needle cartridge (Anvisa 80281110015) at a frequency of 70 Hz and needle depth of 1.0 mm. A triamcinolone acetonide (TAC) solution was placed in a sterile receptacle and loaded onto the cartridge by capillarity. We produced micropunctures of the skin with the medication-soaked needles until the affected area was covered by a bloody dew. Case 1: J.C.V., a male, with a diagnosis of AA in patches was treated with 1-monthly session with 2.5 mg\/mL TAC delivered by MMP\u00ae (4 sessions in total). Case 2: L.M.V., a 78-year-old female with a diagnosis of AA was treated with 1-monthly session with 10 mg\/mL TAC delivered by MMP\u00ae (4 sessions in total). MMP\u00ae is a novel technique that combines microneedling with drug delivery, and it could be used to deliver IL TAC to AA patients. This technique promotes a more uniform absorption of corticosteroids than traditional treatment methods of AA. <\/jats:p>","DOI":"10.1159\/000506314","type":"journal-article","created":{"date-parts":[[2020,6,18]],"date-time":"2020-06-18T21:00:31Z","timestamp":1592514031000},"page":"229-234","source":"Crossref","is-referenced-by-count":7,"title":["Successful Treatment of Alopecia Areata Patches with Triamcinolone Acetonide Using MMP\u00ae: Report of 2 Cases"],"prefix":"10.1159","volume":"6","author":[{"given":"Marina","family":"Barletta","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciana","family":"Gasques","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2020,6,18]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.4103\/ijt.ijt_99_17"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.4103\/0974-2077.129989"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.14408"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.4103\/0974-7753.114700"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.24966\/CDT-8771\/100006"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jisp.2017.10.002"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.13950"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1991.01680020102014"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2011.02137.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2005.02633.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2017.08.019"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1159\/000500709"}],"container-title":["Skin Appendage Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/506314","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/506314","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:49:15Z","timestamp":1745423355000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000506314"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":12,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,7,17]]},"published-print":{"date-parts":[[2020,7,15]]}},"URL":"https:\/\/doi.org\/10.1159\/000506314","archive":["Portico"],"relation":{},"ISSN":["2296-9195","2296-9160"],"issn-type":[{"value":"2296-9195","type":"print"},{"value":"2296-9160","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020]]}}}