{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T14:05:49Z","timestamp":1791468349453,"version":"4.3.4"},"reference-count":14,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dement Geriatr Cogn Disord"],"published-print":{"date-parts":[[2020]]},"abstract":"<b><i>Introduction:<\/i><\/b> The Addenbrooke\u2019s Cognitive Examination III (ACE-III) (2012) is a brief cognitive battery that assesses five sub-domains of cognition (attention and orientation, memory, verbal fluency, language, and visuospatial abilities) which are commonly impaired in dementia. <b><i>Objective:<\/i><\/b> We aimed to validate the Egyptian-Arabic ACE-III in dementia patients, and to provide cut-off scores for the ACE-III in diagnosing dementia in Egyptian-Arabic speakers. <b><i>Methods:<\/i><\/b> We included 37 patients with dementia (Alzheimer\u2019s disease, <i>n<\/i> = 25, vascular dementia, <i>n<\/i> = 8, and dementia with Lewy bodies, <i>n<\/i> = 4) and 43 controls. <b><i>Results:<\/i><\/b> There was a statistically significant difference (<i>p<\/i> &#x3c; 0.001) in the total ACE-III score between dementia patients (mean 49.81 \u00b1 18.58) and controls (mean 84.84 \u00b1 6.36). There was also a statistically significant difference between dementia patients and controls in all sub-score domains of the ACE-III (<i>p<\/i> &#x3c; 0.001). Using a receiver operator characteristic curve, the optimal cut-off score for dementia on the ACE-III total score was 72, (89% sensitivity, 95% specificity, 92% accuracy). <b><i>Conclusions:<\/i><\/b> The results of this study provide objective validation of the Egyptian-Arabic version of the ACE-III as a screening tool for dementia, with high sensitivity, specificity, and accuracy comparable to other translated versions of the ACE-III.<\/jats:p>","DOI":"10.1159\/000507758","type":"journal-article","created":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T17:00:57Z","timestamp":1589562057000},"page":"179-184","source":"Crossref","is-referenced-by-count":15,"title":["Validation of the Egyptian-Arabic Version of the Addenbrooke\u2019s Cognitive Examination III (ACE-III) in Diagnosing Dementia"],"prefix":"10.1159","volume":"49","author":[{"given":"Tarik","family":"Qassem","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed\u00a0S.","family":"Khater","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamer","family":"Emara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doha","family":"Rasheedy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heba\u00a0M.","family":"Tawfik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed\u00a0S.","family":"Mohammedin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad\u00a0F.","family":"Tolba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karim","family":"Abdel\u00a0Aziz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2020,5,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1159\/000351671"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.2147\/NDT.S127605"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.dadm.2018.06.003"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/01.XME.0000457267.05731.0f"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2011.03.005"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.43.11.2412-a"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1975.00490510088009"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(75)90026-6"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/gps.1610"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3988\/jcn.2019.15.3.313"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1159\/000495107"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-019-1120-4"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.4306\/pi.2016.13.5.571"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.nrl.2014.05.004"}],"container-title":["Dementia and Geriatric Cognitive Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/507758","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/507758","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T12:03:40Z","timestamp":1745409820000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000507758"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":14,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2020,10,6]]},"published-print":{"date-parts":[[2020,10,13]]}},"URL":"https:\/\/doi.org\/10.1159\/000507758","archive":["Portico"],"relation":{},"ISSN":["1420-8008","1421-9824"],"issn-type":[{"value":"1420-8008","type":"print"},{"value":"1421-9824","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020]]}}}