{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T16:01:02Z","timestamp":1788883262286,"version":"build-2803163510"},"reference-count":22,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Nutr Metab"],"published-print":{"date-parts":[[2020]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Objective:&lt;\/i&gt;&lt;\/b&gt; Given the association between diabetes suppression and inhibition of diet-induced elevation in glucose and insulin, we investigated the effects of adding glucomannan to rice gruel on pre- and postprandial glucose and insulin concentrations. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; A total of 25 Japanese subjects without a history of diabetes or gastrointestinal disease (all males; aged 37\u201360 years; body mass index 20.4\u201331.6) participated in this study. Subjects received a 75-g oral glucose tolerance test (75gOGTT) and rice gruel containing 0, 0.4, or 0.8% of glucomannan. Blood samples were then obtained at preload and at 30, 60, and 120 min after receiving 75 g of glucose or rice gruel with or without glucomannan. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; After the 75gOGTT, 8 subjects had normal glucose tolerance (NGT), whereas 17 showed a borderline pattern. Moreover, our data showed that greater amounts of glucomannan promoted lesser 30-min postload plasma glucose and insulin levels, with differences being larger in the borderline group than in the NGT group. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; Glucomannan dose-dependently inhibited the rice gruel-induced increase in 30-min postprandial plasma glucose and insulin levels. Furthermore, greater inhibitory effects on glucose and insulin elevation were observed in the borderline group than in the NGT group. <\/jats:p>","DOI":"10.1159\/000508674","type":"journal-article","created":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T21:00:46Z","timestamp":1594674046000},"page":"259-267","source":"Crossref","is-referenced-by-count":8,"title":["Glucomannan Inhibits Rice Gruel-Induced Increases in Plasma Glucose and Insulin Levels"],"prefix":"10.1159","volume":"76","author":[{"given":"Akihiro","family":"Yoshida","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takao","family":"Kimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuhiko","family":"Tsunekawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osamu","family":"Araki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazumi","family":"Ushiki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirotaka","family":"Ishigaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshifumi","family":"Shoho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Itsumi","family":"Suda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suguru","family":"Hiramoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masami","family":"Murakami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2020,7,13]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.21.3.C11"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)00618-8"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.22.6.920"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.2337\/dc05-2179"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)12131-1"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.23.8.1097"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.2147\/PPA.S84268"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60222-1"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200363100-00002"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/BF00262220"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.1994.tb00277.x"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1080\/07315724.2003.10719273"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/610908"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jada.2004.09.020"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1186\/s12906-015-0935-6"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2013.02.008"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2016.02.014"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2016.07.098"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1111\/j.2040-1124.2010.00074.x"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.6124.1392"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.3233\/s12349-013-0121-7"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.21.7.1167"}],"container-title":["Annals of Nutrition and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/508674","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/508674","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:13:38Z","timestamp":1745424818000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000508674"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":22,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,12,2]]},"published-print":{"date-parts":[[2020,12,8]]}},"URL":"https:\/\/doi.org\/10.1159\/000508674","archive":["Portico"],"relation":{},"ISSN":["0250-6807","1421-9697"],"issn-type":[{"value":"0250-6807","type":"print"},{"value":"1421-9697","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020]]}}}