{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:20:24Z","timestamp":1756383624296,"version":"3.40.4"},"reference-count":9,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2020,10,2]],"date-time":"2020-10-02T00:00:00Z","timestamp":1601596800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2020,10,2]],"date-time":"2020-10-02T00:00:00Z","timestamp":1601596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Neurol"],"abstract":"<jats:p>Stiff person syndrome (SPS) is a rare neurologic disorder, characterized by muscle rigidity and spasms. Anti-glutamic acid decarboxylase (anti-GAD) antibodies are associated with the classic form of SPS, while antibodies against amphiphysin are associated with the paraneoplastic form of the disease. We present the case of a patient with paraneoplastic SPS, presenting with muscle cramps of lower extremities that progressed to severe muscle rigidity and spasms, associated with a right breast tumor and positive anti-amphiphysin antibodies. Paraneoplastic SPS is a rare neurological disorder, challenging for the physicians both to diagnose and treat. <\/jats:p>","DOI":"10.1159\/000508942","type":"journal-article","created":{"date-parts":[[2020,10,2]],"date-time":"2020-10-02T21:00:58Z","timestamp":1601672458000},"page":"339-347","source":"Crossref","is-referenced-by-count":2,"title":["Paraneoplastic Stiff Person Syndrome in Early-Stage Breast Cancer with Positive Anti-Amphiphysin Antibodies"],"prefix":"10.1159","volume":"12","author":[{"given":"Vitalie","family":"Vacaras","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enia\u00a0Eleonora","family":"Cucu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roxana","family":"Radu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dafin\u00a0Fior","family":"Muresanu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2020,10,2]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.427"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.2340\/16501977-2089"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/278065"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.50.1.94"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0027-9684(15)30757-4"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s11940-009-0013-9"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.67.1.126"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.65.5.633"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1186\/s40164-016-0058-x"}],"container-title":["Case Reports in Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/508942","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/508942","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:41:33Z","timestamp":1745422893000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000508942"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,2]]},"references-count":9,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,1,7]]}},"URL":"https:\/\/doi.org\/10.1159\/000508942","archive":["Portico"],"relation":{},"ISSN":["1662-680X"],"issn-type":[{"type":"electronic","value":"1662-680X"}],"subject":[],"published":{"date-parts":[[2020,10,2]]}}}