{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T20:13:56Z","timestamp":1773087236980,"version":"3.50.1"},"reference-count":20,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T00:00:00Z","timestamp":1604016000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T00:00:00Z","timestamp":1604016000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Neurol"],"abstract":"<jats:p>Lymphoma is a prevalent type of lymphoid tissue malignancy that is seldom associated with Guillain-Barr\u00e9 syndrome (GBS). In the majority of instances, both Hodgkin\u2019s and non-Hodgkin\u2019s lymphoma are not proceeded by GBS. Here, we report on a case of a young patient with a manifestation and investigation suggestive of GBS, signaling an unconfirmed diagnosis of Hodgkin\u2019s lymphoma. A cerebrospinal fluid test revealed an albuminocytological dissociation with a noteworthy rise in protein (2.32 g\/L). The patient was initiated on intravenous immunoglobulin (IVIG) treatment and then showed dramatic improvement after the third dose of IVIG. His constitutional presentation alongside high inflammatory labs prompted further investigation. An enhanced pan-computed tomography scan showed multiple enlarged mediastinal and hilar lymph nodes that were confirmed as Hodgkin\u2019s lymphoma after biopsy. Brentuximab was initiated immediately after IVIG therapy. This case highlights consideration of Hodgkin\u2019s lymphoma as a differential diagnosis under the auspices of GBS. <\/jats:p>","DOI":"10.1159\/000509681","type":"journal-article","created":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T22:00:39Z","timestamp":1604095239000},"page":"365-372","source":"Crossref","is-referenced-by-count":4,"title":["Guillain-Barr\u00e9 Syndrome Heralding the Diagnosis of Hodgkin Lymphoma: A Case Report"],"prefix":"10.1159","volume":"12","author":[{"given":"Alawi\u00a0Aqel","family":"Al-Attas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdulrahman\u00a0Yousef","family":"Aldayel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara\u00a0Abdullah","family":"Al\u00a0Najjar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saleh\u00a0Mansoor","family":"Alkhonezan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2020,10,30]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-801368-7.00021-1"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1991.tb03957.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/mus.23464"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2013.01.005"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2377-13-195"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20163"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2007.125930"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.5152\/TurkPediatriArs.2018.4763"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-03-537506"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.nrl.2011.10.009"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410010107"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-510X(80)80003-7"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.8.7.575"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199009273231308"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1093\/milmed\/148.6.512"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)00339-1"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.3390\/nu10101531"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1002\/mus.25439"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(08)70215-1"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410410608"}],"container-title":["Case Reports in Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/509681","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/509681","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:49:25Z","timestamp":1745423365000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000509681"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,30]]},"references-count":20,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,1,7]]}},"URL":"https:\/\/doi.org\/10.1159\/000509681","archive":["Portico"],"relation":{},"ISSN":["1662-680X"],"issn-type":[{"value":"1662-680X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,30]]}}}