{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T03:31:02Z","timestamp":1747193462324,"version":"3.40.5"},"reference-count":14,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2021,2,25]],"date-time":"2021-02-25T00:00:00Z","timestamp":1614211200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2021,2,25]],"date-time":"2021-02-25T00:00:00Z","timestamp":1614211200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Oncol"],"abstract":"<jats:p>Primary mediastinal sarcomas are extremely rare. Additionally, mediastinal leiomyosarcomas account for approximately 9% of mediastinal sarcoma cases. Until date, only few cases of anterior mediastinal leiomyosarcomas have been reported. Herein, we report a case of an 85-year-old female with an anterior mediastinal mass of 15 mm. Histological examination revealed spindle tumor cells showing a fascicular growth pattern. Immunohistochemically, the tumor cells were focal positive for desmin, calponin, and \u03b1-smooth muscle actin. The pathological diagnosis was leiomyosarcoma. In conclusion, we encountered a case of a very rare leiomyosarcoma that occurred in the anterior mediastinum, and our report may contribute to the understanding of this disease. <\/jats:p>","DOI":"10.1159\/000509772","type":"journal-article","created":{"date-parts":[[2021,3,23]],"date-time":"2021-03-23T16:40:25Z","timestamp":1616517625000},"page":"101-106","source":"Crossref","is-referenced-by-count":0,"title":["Anterior Mediastinal Leiomyosarcoma: A Case Report and Literature Review"],"prefix":"10.1159","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1528-1939","authenticated-orcid":false,"given":"Akira","family":"Ishikawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuya","family":"Kuraoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junichi","family":"Zaitsu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihisa","family":"Saito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Kamigaichi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2809-4833","authenticated-orcid":false,"given":"Takeshi","family":"Mimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshinori","family":"Yamashita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyomi","family":"Taniyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2021,2,25]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21551"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19920701)70:1%3c114::aid-cncr2820700119%3e3.0.co;2-u"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19810815)48:4%3c1022::aid-cncr2820480429%3e3.0.co;2-5"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200201000-00002"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(98)70333-2"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra041866"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcu221"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s007950300007"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2014.10.036"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.5761\/atcs.cr.11.01710"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19941015)74:8%3c2251::aid-cncr2820740808%3e3.0.co;2-4"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3892\/mco.2020.1977"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19840601)53:11%3c2553::aid-cncr2820531130%3e3.0.co;2-s"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-015-1832-6"}],"container-title":["Case Reports in Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/509772","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/509772","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:50:04Z","timestamp":1745423404000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000509772"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,25]]},"references-count":14,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021,5,3]]}},"URL":"https:\/\/doi.org\/10.1159\/000509772","archive":["Portico"],"relation":{},"ISSN":["1662-6575"],"issn-type":[{"type":"electronic","value":"1662-6575"}],"subject":[],"published":{"date-parts":[[2021,2,25]]}}}