{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:25:50Z","timestamp":1745468750309,"version":"3.40.4"},"reference-count":19,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Haematol"],"published-print":{"date-parts":[[2023]]},"abstract":"<jats:p>The translocation t(8;9) produces the fusion gene PCM1-JAK2, resulting in the continuous activation of the JAK2 tyrosine kinase. Myelodysplastic\/myeloproliferative neoplasms are the most common disease with t(8;9)\/PCM1-JAK2. Individuals with this abnormality have similar features, and JAK2 kinase inhibitor (ruxolitinib) is an effective treatment of the condition. The long-term remission results of ruxolitinib are varied. It is important to determine the response to ruxolitinib. Here, we describe a patient who has been diagnosed with eosinophilia-associated myeloproliferative neoplasm with t(8;9)(p21;p24). This patient has achieved sustained response for &gt;1 year since the administration of ruxolitinib. <\/jats:p>","DOI":"10.1159\/000510281","type":"journal-article","created":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T21:01:16Z","timestamp":1691701276000},"page":"397-400","source":"Crossref","is-referenced-by-count":0,"title":["Sustained Response to Ruxolitinib of Eosinophilia-Associated Myeloproliferative Neoplasm with Translocation t(8;9)(p21;p24)"],"prefix":"10.1159","volume":"146","author":[{"given":"Ping","family":"Cai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suhui","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lijuan","family":"Duan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Huo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Depei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suning","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruyu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaofei","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2023,8,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1208850"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3343\/alm.2016.36.1.79"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3343\/alm.2018.38.5.492"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-04-4263"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s12185-008-0113-4"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-013-1695-3"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1038\/s41379-018-0165-9"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-014-2221-y"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-03-487348"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1517\/14728222.2011.538683"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-10-607341"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2005.07.020"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2403879"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.2010.01525.x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-06-433821"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3109\/10428194.2012.661856"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2012.067959"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.12392"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.46.4370"}],"container-title":["Acta Haematologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/aha\/article-pdf\/146\/5\/397\/4014238\/000510281.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/aha\/article-pdf\/146\/5\/397\/4014238\/000510281.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:54:49Z","timestamp":1745423689000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000510281"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":19,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2023,10,3]]}},"URL":"https:\/\/doi.org\/10.1159\/000510281","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.23918391","asserted-by":"subject"}]},"ISSN":["0001-5792","1421-9662"],"issn-type":[{"type":"print","value":"0001-5792"},{"type":"electronic","value":"1421-9662"}],"subject":[],"published":{"date-parts":[[2023]]}}}