{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T02:07:24Z","timestamp":1777860444137,"version":"3.51.4"},"reference-count":17,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T00:00:00Z","timestamp":1600646400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T00:00:00Z","timestamp":1600646400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Oncol"],"abstract":"<jats:p>A 40-year-old man had been treated for Beh\u00e7et\u2019s disease (BD) with cyclosporine A (CsA) for 14 years. He presented multiple lymphadenopathies with fever. Histological examination of surgical biopsy showed other iatrogenic immunodeficiency-associated lymphoproliferative disorders, diffuse large B-cell lymphoma type with positivity for Epstein-Barr virus encoding RNA-1 (EBER-1). &lt;i&gt;BCL2-IgH&lt;\/i&gt;, &lt;i&gt;BCL6-IgH&lt;\/i&gt;, and &lt;i&gt;MYC-IgH&lt;\/i&gt; translocations were not detected. CsA was stopped, and R-CHOP therapy was initiated. However, his lymphoma was chemotherapy resistant and rapidly progressed. To the best of our knowledge, this is the first case of diffuse large B-cell lymphoma that occurred in a BD patient treated with CsA reported in English. Both BD and CsA are associated with the pathogenesis of lymphoma. We also describe extremely rare cases in the form of a literature review. <\/jats:p>","DOI":"10.1159\/000510362","type":"journal-article","created":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T21:00:55Z","timestamp":1600722055000},"page":"1145-1151","source":"Crossref","is-referenced-by-count":3,"title":["Other Iatrogenic Immunodeficiency-Associated Lymphoproliferative Disorders, Diffuse Large B-Cell Lymphoma Type, in a Patient with Beh\u00e7et\u2019s Disease Treated with Cyclosporine A"],"prefix":"10.1159","volume":"13","author":[{"given":"Yuka","family":"Urano","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8035-791X","authenticated-orcid":false,"given":"Rintaro","family":"Ohe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akane","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takanobu","family":"Kabasawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazushi","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takumi","family":"Kitaoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuyuki","family":"Tamazawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naing Ye","family":"Aung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aya","family":"Utsunomiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomomi","family":"Toubai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenichi","family":"Ishizawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2020,9,21]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s100670170036"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-009-1319-3"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/1756-185X.12269"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-0360"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.9167-17"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.2176\/nmc.45.586"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-09-297879"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2016.09.004"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/pas.0000000000001071"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1186\/s13000-020-00954-8"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2006.03988.x"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1159\/000095044"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-0978"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.46.8058"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3960\/jslrt.52.211"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3960\/jslrt.19007"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.2012.02307.x"}],"container-title":["Case Reports in Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/510362","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/510362","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T15:55:25Z","timestamp":1745423725000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000510362"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,21]]},"references-count":17,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,1,6]]}},"URL":"https:\/\/doi.org\/10.1159\/000510362","archive":["Portico"],"relation":{},"ISSN":["1662-6575"],"issn-type":[{"value":"1662-6575","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,21]]}}}