{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T20:19:42Z","timestamp":1778876382837,"version":"3.51.4"},"reference-count":14,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Obes Facts"],"published-print":{"date-parts":[[2020]]},"abstract":"<b><i>Objective:<\/i><\/b> Obesity is a major risk factor for becoming seriously ill with the 2019 novel coronavirus (COVID-19). One difficulty faced by clinicians and by patients is the unknown time frame of hospitalization until discharge of symptomatic patients. <b><i>Methods:<\/i><\/b> We followed 34 patients with laboratory-confirmed COVID-19 infection who recovered from<b><i><\/i><\/b>the infection. All diagnoses were given using semi-quantitative RT-PCR on nasopharyngeal swabs. Envelope protein gene (E), RNA-dependent RNA polymerase gene (RdRP), and nucleocapsid gene (N) were measured by RT-PCR. Weight was measured and height was self-reported. <b><i>Results:<\/i><\/b> Mean \u00b1 SD age was 51.8 \u00b1 16.7 years. Mean \u00b1 SD body mass index (BMI) was 27.4 \u00b1 4.7 kg\/m<sup>2<\/sup>. 26% (9\/34) had obesity, with BMI above 30 kg\/m<sup>2<\/sup>. Fifteen patients had BMI between 25 and 29.9 kg\/m<sup>2<\/sup>. The mean length of hospital stay was longer for those with a BMI &#x3e;25 kg\/m<sup>2<\/sup> (<i>n<\/i> = 24) than for those with a normal BMI (19.2 vs. 16.0 days, <i>p<\/i> = 0.08). Comparing people with obesity (BMI &#x3e;30 kg\/m<sup>2<\/sup> or above) to those without obesity, the difference was larger (20.6 vs. 16.0 days, <i>p<\/i> = 0.06). A trend for correlation between body weight and the time to negative detection of RdRp gene was found (<i>r<\/i> = 0.33, <i>p<\/i> = 0.09). <b><i>Conclusions:<\/i><\/b> Our results highlight the need for priority of early detection and testing, and early therapy for people with obesity and COVID-19 infections. <\/jats:p>","DOI":"10.1159\/000511738","type":"journal-article","created":{"date-parts":[[2020,9,29]],"date-time":"2020-09-29T21:02:01Z","timestamp":1601413321000},"page":"528-533","source":"Crossref","is-referenced-by-count":11,"title":["A Time Frame for Testing Negative for SARS-COV2 in People with Obesity"],"prefix":"10.1159","volume":"13","author":[{"given":"Dror","family":"Dicker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaul","family":"Lev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamar","family":"Gottesman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatiana","family":"Kournos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maya","family":"Dotan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nina","family":"Ashorov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dana","family":"Marcoviciu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Golan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2020,9,29]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2020.02.034"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/oby.22808"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc2010419"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp2009249"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.5394"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/oby.22831"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/oby.22818"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.1583"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2020.04.063"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2020.25.3.2000045"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3945\/an.115.010207"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002\/oby.22844"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.120.047659"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.01071"}],"container-title":["Obesity Facts"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/511738","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/511738","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:10:00Z","timestamp":1745424600000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000511738"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":14,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2020,10,30]]},"published-print":{"date-parts":[[2020,10,31]]}},"URL":"https:\/\/doi.org\/10.1159\/000511738","archive":["Portico"],"relation":{},"ISSN":["1662-4025","1662-4033"],"issn-type":[{"value":"1662-4025","type":"print"},{"value":"1662-4033","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020]]}}}